Oncology & Cancer
Vaccine for HER2 breast cancer shows early promise
A vaccine developed by Duke Cancer Institute researchers has shown early promise in targeting the HER2 protein that fuels a deadly form of breast cancer.
Mar 12, 2019
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News tagged with her2 protein
Oncology & Cancer
Immunotherapy with CAR T cells results in exceptional patient recovery
In a clinical trial evaluating a novel immunotherapy option for cancer treatment, a child with rhabdomyosarcoma, a form of muscle cancer, that had spread to the bone marrow, showed no detectable cancer following treatment ...
Jul 15, 2020
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165
Oncology & Cancer
New path to overcoming drug resistance in HER2-positive breast cancer
The HER2 protein, which encourages the growth of cancer cells, is present in about 20% of all breast cancers. While HER2-positive breast cancers tend to be very aggressive, today the prognosis is generally very good, thanks ...
Feb 13, 2019
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Oncology & Cancer
Antibody-drug conjugate shows impressive activity in patients with non-small cell lung cancer with mutation in HER2 gene
More than half of patients with non-small cell lung cancer (NSCLC) bearing a mutation in the HER2 gene had their tumors stop growing or shrink for an extended time after treatment with a drug that hitches a chemotherapy agent ...
Sep 19, 2021
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Oncology & Cancer
Research team identifies master switch for cancer-causing HER2 protein
Herceptin has been touted as a wonder drug for women with HER2-positive breast cancer, an aggressive form of the disease that is fueled by excess production of the HER2 protein. However, not all of these patients respond ...
Apr 28, 2015
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Oncology & Cancer
Breast cancer treatment shows benefit for women with small, localized disease
Memorial Sloan-Kettering Cancer Center physician-scientists report that women with small, node-negative, HER2-positive breast cancer may obtain a significant benefit from adjuvant chemotherapy with trastuzumab (Herceptin), ...
Jun 28, 2011
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Oncology & Cancer
New research challenges notion of using Herceptin only for HER2-positive breast cancer
New research from the University of Michigan Comprehensive Cancer Center finds that the protein HER2 plays a role even in breast cancers that would traditionally be categorized as HER2-negative – and that the drug Herceptin, ...
Feb 26, 2013
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Oncology & Cancer
Study finds breast cancers with low levels of HER2 protein are not a distinct subtype of the disease
The treatment of breast cancer abounding in the protein HER2 was revolutionized with the introduction of drugs like trastuzumab (Herceptin) that target the protein. When researchers discovered that breast cancers with lower ...
Jun 24, 2022
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Oncology & Cancer
Vaccine shows promising results for early-stage breast cancer patients
Deregulation and inhibition of the immune system contributes to cancer development. Many therapeutic strategies aim to re-stimulate the immune system to recognize cancer cells and target them for destruction. Researchers ...
Jan 3, 2017
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Oncology & Cancer
Imaging technique could help focus breast cancer treatment
Cancer Research UK scientists have used imaging techniques as a new way to identify patients who could benefit from certain breast cancer treatments, according to a study published in Oncotarget.
Jul 8, 2016
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