Diseases, Conditions, Syndromes

Vaccine shows promise against herpes virus

A genetically edited form of a herpes simplex virus—rewired to keep it from taking refuge in the nervous system and eluding an immune response—has outperformed a leading vaccine candidate in a new study from the University ...

Alzheimer's disease & dementia

3-D brain-like tissue model links Alzheimer's disease with herpes

Engineers and scientists led by Tufts University used a three-dimensional (3-D) human tissue culture model mimicking the components and conditions in the brain to demonstrate a possible causal relationship between sporadic ...

Diseases, Conditions, Syndromes

Discovery reveals mechanism that turns herpes virus on and off

New research from Dr. Luis M. Schang and his group at the Baker Institute for Animal Health has identified a new mechanism that plays a role in controlling how the herpes virus alternates between dormant and active stages ...

Diseases, Conditions, Syndromes

Fighting the herpes virus

New insights into preventing herpes infections have been published in Nature Communications. Researchers from the Berlin Institute for Medical Systems Biology (BIMSB) at the MDC used single-cell RNA sequencing to better understand ...

Immunology

New vaccine prevents herpes in mice, guinea pigs

Researchers from the Perelman School of Medicine at the University of Pennsylvania have developed a vaccine to protect against genital herpes. Tested on both mice and guinea pigs, the immunization led to "mostly sterilizing ...

Diseases, Conditions, Syndromes

Can a combination immune therapy reduce genital herpes outbreaks?

Yale investigators have shown that the combination of a vaccine and a medicated cream is a promising strategy to dramatically reduce the recurrence of genital herpes. Their study, co-led by researchers at the University of ...

Diseases, Conditions, Syndromes

Clues to building a better herpes vaccine

Efforts to develop an effective vaccine for genital herpes, a common sexually transmitted disease, have largely failed. In a new study published in Nature, Yale researchers explore why, and their findings could lead to a ...

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