Diseases, Conditions, Syndromes

Hitting virus infections where it hurts

Virus infection starts at the cell surface with interactions between viral and host proteins that bind together. Researchers are working on ways to lock out the virus or prevent it from reproducing in the cell by targeting ...

Immunology

Toxin floats on lipid rafts

Helicobacter pylori, the leading cause of peptic ulcer disease and stomach cancer. One factor important to H. pylori infection is the pore-forming toxin VacA. It is thought to gain entry into host cells by binding to specialized ...

Diseases, Conditions, Syndromes

New insight into widespread virus behind birth defects

A Northwestern Medicine study published in Developmental Cell provides new insights into how cytomegalovirus—a common virus in the herpes family—replicates within human cells, and identifies proteins that may be therapeutically ...

Diseases, Conditions, Syndromes

Novel genome platform reveals new HIV targets

Sanford Burnham Prebys Medical Discovery Institute (SBP) researchers have developed the first ever high-throughput, genome-scale imaging-based approach to investigate protein stability. The method has been used to identify ...

Diseases, Conditions, Syndromes

Dengue takes low and slow approach to replication

A new study reveals how dengue virus manages to reproduce itself in an infected person without triggering the body's normal defenses. Duke researchers report that dengue pulls off this hoax by co-opting a specialized structure ...

Diseases, Conditions, Syndromes

Dibenzoazepine found to be effective against resistant hepatitis C

Hepatitis C is caused by a highly infectious virus affecting millions across the globe and can lead to a variety of liver ailments. While the hepatitis C virus (HCV) can sometimes be fought off and cleared by the immune system ...

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