University of Toronto (U of T) researchers have found that cancer cells can enhance tumor growth by hijacking enhancer DNA normally used when tissues and organs are formed. The mechanism, called enhancer reprogramming, occurs ...
Sep 29, 2023
0
66
Many cancers are caused by fusion oncoproteins, molecules that aberrantly form when a rearrangement of DNA results in parts of two different proteins being expressed as one. Several fusion oncoproteins spontaneously form ...
Sep 28, 2023
0
54
A new development in biomedical engineering has led to the creation of a human stomach micro-physiological system (hsMPS), representing a significant leap forward in understanding and treating various gastrointestinal diseases, ...
Sep 27, 2023
0
19
To give cancer treatments the greatest possible chance of success, patients are often treated with multiple drugs that attack the cancer using different mechanisms. A team of researchers has now combined three highly potent ...
Sep 19, 2023
0
63
Zachary Schug, Ph.D., assistant professor in the Molecular and Cellular Oncogenesis Program of the Ellen and Ronald Caplan Cancer Center at The Wistar Institute, has published a new paper in the journal Nature Cancer. Schug's ...
Sep 18, 2023
0
134
Several types of cancer are believed to be linked to alterations of macromolecular structures known as nuclear pore complexes (NPCs). These structures are embedded in the nuclear envelope, a membrane barrier that separates ...
Sep 15, 2023
0
50
Researchers at the University of Arizona Cancer Center discovered a new class of iron-targeting compounds that hamper the proliferation of cultured malignant cells in a laboratory setting. The results of the study were published ...
Sep 11, 2023
0
50
Experts in cell signaling at the Babraham Institute have identified how prostate cancer cells achieve cell growth free from the usual growth cues and regulators. This discovery has implications for potential therapeutics ...
Sep 11, 2023
0
21
A new study published in Nature Genetics led by the Mead Group in the Radcliffe Department of Medicine has demonstrated a previously unknown effect of chronic inflammation on TP53-mutant hematopoietic stem cells.
Sep 8, 2023
0
253
The elucidation of the role of a critical protein in cell biology is paving the way for alternative cancer treatments. By refuting recent challenges that threatened to invalidate their work, a team of KAUST researchers investigating ...
Aug 24, 2023
0
8
