Oncology & Cancer

Faulty DNA repair may lead to BRCA-linked cancers

Error-prone DNA replication and repair may lead to mutations and cancer in individuals who inherit a mutant copy of the BRCA1 gene, according to a new study by Weill Cornell Medicine investigators. The discovery has potential ...

Genetics

Streamlining stem cells to treat macular degeneration

As we age, so do our eyes; most commonly, this involves changes to our vision and new glasses, but there are more severe forms of age-related eye problems. One of these is age-related macular degeneration, which affects the ...

Medical research

Brain organoids develop optic cups that respond to light

Human induced pluripotent stem cells (iPSCs) can be used to generate brain organoids containing an eye structure called the optic cup, according to a study published August 17 in the journal Cell Stem Cell. The organoids ...

Medical research

In a dish, a mouse, crafted from stem cells, begins to form

The tiny mouse embryo has a heart that beats. Its muscles, blood vessels, gut and nervous system are beginning to develop. But this embryo is unusual: It was made in a lab, out of mouse embryonic stem cells, and represents ...

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