In the decade since the genome was sequenced in 2003, scientists and doctors have struggled to answer an all-consuming question: Which DNA mutations cause disease?
Dec 18, 2014
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Widely used for modern biomedical research, zebrafish share more than 70 percent of the human genome and possess the impressive power of regeneration. Dr. Sandra Rieger's research on appendage regeneration and nerve damage ...
Aug 16, 2022
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Cellular senescence, a state of permanent growth arrest, has emerged as a hallmark and fundamental driver of organismal aging. It is regulated by both genetic and epigenetic factors. Despite a few previously reported aging-associated ...
Jan 8, 2021
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An analysis of the DNA of thousands of people who have been infected with the coronavirus, SARS-CoV-2, and shown a positive test for the disease it causes, COVID-19, shows that they have several DNA characteristics in common. ...
Aug 16, 2021
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Researchers from the Chinese Academy of Sciences in Beijing recently reported intriguing new evidence for a possible mouse origin of the Omicron variant. Their paper, posted on the BioRxiv preprint server, was quickly picked ...
In a recently published editorial in the journal Genes & Cancer, researcher Tatsuro Jo from the Japanese Red Cross Nagasaki Genbaku Hospital's Department of Hematology discussed aggressive type adult T-cell leukemia/lymphoma ...
Feb 27, 2023
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Researchers have shown that a variation in the viral genome of COVID-19 improved its ability to infect human cells and helped it become the dominant strain circulating around the world today.
Jul 2, 2020
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Building on earlier pioneering work by researchers at the University of California, San Diego, an international consortium of university researchers has produced the most comprehensive virtual reconstruction of human metabolism ...
Mar 3, 2013
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Human intelligence and behavior require optimal functioning of a large number of genes, which requires enormous evolutionary pressures to maintain. A provocative hypothesis published in a recent set of Science and Society ...
Nov 12, 2012
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Adenoviruses have a linchpin protein that stabilizes their DNA until it reaches the infected cell's nucleus. The protein then detaches from the viral genome, and the virus uncoats. Only then are the genes released into the ...
Dec 21, 2021
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The human genome is the genome of Homo sapiens, which is stored on 23 chromosome pairs. Twenty-two of these are autosomal chromosome pairs, while the remaining pair is sex-determining. The haploid human genome occupies a total of just over 3 billion DNA base pairs. The Human Genome Project (HGP) produced a reference sequence of the euchromatic human genome, which is used worldwide in biomedical sciences.
The haploid human genome contains an estimated 20,000–25,000 protein-coding genes, far fewer than had been expected before its sequencing. In fact, only about 1.5% of the genome codes for proteins, while the rest consists of RNA genes, regulatory sequences, introns and (controversially) "junk" DNA.
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