Immunology

Study shows immune cells have a backup mechanism

The enzyme TBK1 is an important component of the innate immune system that plays a critical role in the defense against viruses. Upon mutation-induced loss of TBK1 function, patients show an increased susceptibility to viral ...

Diseases, Conditions, Syndromes

Chimera viruses can help the fight against lymphomas

Researchers from Instituto de Medicina Molecular (iMM) Lisboa have created a chimera virus that allows the study of molecules to treat cancers caused by human herpes virus infection in mice models of disease.

Diseases, Conditions, Syndromes

Scientists advance understanding of herpesvirus infection

Herpes simplex virus (HSV) infections last a lifetime. Once a person has been infected, the virus can remain dormant (latent) for years before periodically reactivating to cause recurrent disease. This poorly understood cycle ...

Medical research

Cytomegalovirus hijacks human enzyme for replication

More than 60 percent of the world's population is infected with a type of herpes virus called human cytomegalovirus. The virus replicates by commandeering the host cell's metabolism but the details of this maneuver are unclear.

Medications

FDA approves sylvant for multicentric castleman's disease

(HealthDay)—The U.S. Food and Drug Administration has approved Sylvant (siltuximab) to treat patients with multicentric Castleman's disease (MCD), according to a news release issued by the agency today.

Immunology

Herpes virus exploits immune response to bolster infection

Researchers at the University of California, San Diego School of Medicine and colleagues report that the herpes simplex virus type-1 (HSV-1), which affects an estimated 50 to 80 percent of all American adults, exploits an ...

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