News tagged with human papillomavirus

Related topics: cervical cancer , vaccine , women , cancer , centers for disease control and prevention

Early evidence of HPV vaccine impact

(PhysOrg.com) -- In a new study published in Lancet, researchers from Australia report evidence that the vaccine designed to target the human papillomavirus, or HPV, has dramatically dropped the incidence of les ...

Jun 20, 2011
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Researchers develop and test new anti-cancer vaccine

Researchers at Moffitt Cancer Center have developed and tested in mice a synthetic vaccine and found it effective in killing human papillomavirus-derived cancer, a virus linked to cervical cancers among others. The research ...

Jun 08, 2012
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Virus kills breast cancer cells in laboratory

A nondisease-causing virus kills human breast cancer cells in the laboratory, creating opportunities for potential new cancer therapies, according to Penn State College of Medicine researchers who tested the virus on three ...

Sep 22, 2011
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Cervical cancer vaccine shows promise

A vaccine against cervical cancer, being developed by Inovio Pharmaceuticals Inc. of Blue Bell, Pa., produced positive results in a small sample of 18 women.

Oct 12, 2012
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Bioethicist challenges Bachmann on vaccine claim

(AP) -- A prominent bioethicist has offered $10,000 to charity if Republican presidential candidate Michele Bachmann can prove her claim that a vaccination caused mental retardation.

Sep 16, 2011
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Human papillomavirus

Alphapapillomavirus Betapapillomavirus Gammapapillomavirus Mupapillomavirus Nupapillomavirus

A human papillomavirus (HPV) is a papillomavirus that infects the epidermis and mucous membranes of humans. HPV can lead to cancers of the cervix, vulva, vagina, and anus in women. In men, it can lead to cancers of the anus and penis.

Approximately 130 HPV types have been identified. Some HPV types can cause warts (verrucae), but those types don't cause cancer. Other types can cause cancer, but those types don't cause warts. Other types have no symptoms and are harmless. Most people who become infected with HPV do not know they have it.

About 30-40 HPV types are typically transmitted through sexual contact and infect the anogenital region. Some sexually transmitted HPV types may cause genital warts. Persistent infection with "high-risk" HPV types—different from the ones that cause warts—may progress to precancerous lesions and invasive cancer. HPV infection is a cause of nearly all cases of cervical cancer. However most infections with these types do not cause disease.

Most HPV infections in young females are temporary and have little long-term significance. 70% of infections are gone in 1 year and 90% in 2 years.

A cervical Papanicolaou (Pap) test is used to detect abnormal cells which may develop into cancer. A cervical examination also detects warts and other abnormal growths which become visible as white patches of skin after they are washed with acetic acid. Abnormal and cancerous areas can be removed with a simple procedure, typically with a cauterizing loop.

Pap smears have reduced the incidence and fatalities of cervical cancer in the developed world, but even so there were 11,000 cases and 3,900 deaths in the U.S. in 2008. Cervical cancer has substantial mortality in resource-poor areas; worldwide, there are 490,000 cases and 270,000 deaths.

HPV vaccines, Gardasil and Cervarix, which prevent infection with the HPV types (16 and 18) that cause 70% of cervical cancer, may lead to further decreases.

This text uses material from Wikipedia licensed under CC BY-SA