Medical research

A new wave of antimalarial drugs

Malaria caused by the parasite Plasmodium falciparum remains a major public health problem worldwide. As a continuation of previous research targeting Hsp90, a universal molecular chaperone performing vital functions both ...

Diseases, Conditions, Syndromes

High-throughput screen identifies potential henipavirus drug target

The closely related Hendra and Nipah viruses (referred to jointly as henipaviruses) are deadly cousins of the more common mumps, measles, and respiratory syncytial viruses, all members of the paramyxovirus family. Henipavirus ...

Medical research

Researchers test new pathogen detection technology

Patients who are undergoing treatment for diseases such as cancer often face the added challenge of a compromised immune system, which can be a toll both of their condition and the drugs used to treat it, leaving them vulnerable ...

Medical research

Study creates cell immunity to parasite that infects 50 million

There are two common approaches to protecting humans from infectious disease: Targeting pathogens and parasites with medicines like antibiotics, or dealing with the conditions that allow transmission. A paper published today ...

Medical research

Team improves its sepsis therapeutic device

Last year, a Wyss Institute team of scientists described the development of a new device to treat sepsis that works by mimicking our spleen. It cleanses pathogens and toxins from blood circulating through a dialysis-like ...

Diseases, Conditions, Syndromes

Scientific curiosity and preparedness for emerging pathogen outbreaks

An essay published on July 14th in PLOS Pathogens' new "Research Matters" series reflects on a career path that started with the study of a somewhat obscure mouse virus mice and ended up at the frontline of the SARS and MERS ...

Medical research

Re-booting the human gut

For decades, American travelers to international destinations have been plagued by acute gastrointestinal illnesses that can arise from travel to other countries. The Center for Disease Control (CDC) warns that depending ...

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