Neuroscience
First patients dosed with 'gene silencing' drug for Huntington's disease
The first few patients have received doses of an experimental RNA-targeting drug for Huntington's disease, it was announced today.
Oct 19, 2015
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News tagged with huntingtin gene
Neuroscience
CRISPR/Cas9 gene editing reverses Huntington's in mouse model
Disrupting a problematic gene in brain cells can reverse Huntington's disease pathology and motor symptoms in a mouse model of the inherited neurological disorder, scientists report.
Jun 19, 2017
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Neuroscience
Scientists move closer to treatment for Huntington's disease
A new variant of the gene-editing CRISPR/Cas9 system is safer and more specific than versions previously used in early research towards a treatment for Huntington's disease, shows research published today in Frontiers in ...
Feb 26, 2018
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Neuroscience
New roles found for Huntington's disease protein
A Duke University research team has identified a new function of a gene called huntingtin, a mutation of which underlies the progressive neurodegenerative disorder known as Huntington's Disease.
Jan 21, 2020
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Neuroscience
Huntington's disease gene dispensable in adult mice
Adult mice don't need the gene that, when mutated in humans, causes the inherited neurodegenerative disorder Huntington's disease.
Mar 7, 2016
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Neuroscience
Is Huntington's disease more common than we thought?
More people may have the potential to develop Huntington's disease than previously thought, according to a study published in the June 22, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology. ...
Jun 22, 2016
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Neuroscience
Novel mouse model provides insight into rare neurodegenerative disease
New research sheds light on common pathogenic mechanisms shared by Huntington's disease (HD) and HD-like disorders. The study, published by Cell Press in the May 12, 2011, issue of the journal Neuron, uses a new transgenic ...
May 11, 2011
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Neuroscience
Powerful new approach helps understand molecular alterations in neurological disease
Neurological diseases are typically associated with a multitude of molecular changes. But out of these thousands of changes in gene expression, which ones are actually driving the disease? To answer this question, a team ...
Jun 20, 2018
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Genetics
Scientists tackle Huntington's disease by targeting mutant gene
Huntington's disease is an inherited, neurodegenerative disorder that usually appears in mid-adult life and leads to uncoordinated body movements and cognitive decline. The disease is due to multiple repetitions of a deoxyribonucleic ...
Nov 6, 2012
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Neuroscience
Study suggests potential therapy for Huntington's disease
A new study published in the Proceedings of the National Academy of Sciences (PNAS) suggests that Huntington's disease may take effect much earlier in life than was previously believed, and that a new drug may be key in controlling ...
Sep 5, 2018
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