Regulatory enzyme overexpression may protect against neurodegeneration in Huntington's disease
Treatment that increases brain levels of an important regulatory enzyme may slow the loss of brain cells that characterizes Huntington's disease (HD) and other neurodegenerative disorders. In a report receiving advance online ...
Neuroscience
Dec 18, 2011 |
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Researchers find controlling element of Huntington's disease
A three molecule complex may be a target for treating Huntington's disease, a genetic disorder affecting the brain. This finding by an international research team including scientists from the German Center for Neurodegenerative ...
Diseases, Conditions, Syndromes
Feb 26, 2013 |
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Scientists correct Huntington's disease mutation in induced pluripotent stem cells
Johns Hopkins researchers, working with an international consortium, say they have generated stem cells from skin cells from a person with a severe, early-onset form of Huntington's disease (HD), and turned them into neurons ...
Medical research
Jun 28, 2012 |
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Two proteins offer a 'clearer' way to treat Huntington's disease
In a paper published in the July 11 online issue of Science Translational Medicine, researchers at the University of California, San Diego School of Medicine have identified two key regulatory proteins critic ...
Neuroscience
Jul 11, 2012 |
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Study finds transcriptional biomarker for Huntington's disease
Huntington's disease, a devastating genetic disorder that causes degeneration of nerve cells in the brain, affects more than 15,000 Americans, and at least 150,000 are at risk of developing the disease. There is no known ...
Medical research
Oct 03, 2011 |
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New discovery in fight against Huntington's disease
Researchers at National University of Ireland Galway have made a significant scientific discovery in the fight against Huntington's disease. The novel findings are published 21 February in the online, open access journal ...
Parkinson's & Movement disorders
Feb 21, 2012 |
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Researchers restore neuron function to brains damaged by Huntington's disease
Researchers from South Korea, Sweden, and the United States have collaborated on a project to restore neuron function to parts of the brain damaged by Huntington's disease (HD) by successfully transplanting HD-induced pluripotent ...
Neuroscience
May 29, 2012 |
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Observations refute widely held view on causal mechanism in amyotrophic lateral sclerosis
In science, refuting a hypothesis can be as significant as proving one, all the more so in research aimed at elucidating how diseases proceed with a view toward preventing, treating, or curing them. Such a ...
Diseases, Conditions, Syndromes
Feb 29, 2012 |
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Investigators achieve important step toward treating Huntington's disease
A team of researchers at the UC Davis Institute for Regenerative Cures has developed a technique for using stem cells to deliver therapy that specifically targets the genetic abnormality found in Huntington's disease, a hereditary ...
Neuroscience
Jan 19, 2012 |
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New knowledge on the pharmacology of dopamine stabilizers
A study from Karolinska Institutet in Sweden shows that a new drug for Huntington's disease – pridopidine or dopamine stabiliser ACR16 – might operate via previously unknown mechanisms of action. Researchers have ...
Psychology & Psychiatry
Feb 24, 2012 |
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Speeding up Huntington's research
(Medical Xpress) -- Human brain cells showing aspects of Huntington’s Disease have been developed, opening up new research pathways for treating the fatal disorder.
Neuroscience
Jul 09, 2012 |
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Device implanted in brain has therapeutic potential for Huntington's disease
Studies suggest that neurotrophic factors, which play a role in the development and survival of neurons, have significant therapeutic and restorative potential for neurologic diseases such as Huntington's ...
Neuroscience
Jun 18, 2012 |
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Proposed drug may reverse Huntington's disease symptoms
With a single drug treatment, researchers at the Ludwig Institute for Cancer Research at the University of California, San Diego School of Medicine can silence the mutated gene responsible for Huntington's ...
Neuroscience
Jun 20, 2012 |
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Melatonin delays onset, reduces deaths in mouse model of Huntington's disease
Melatonin, best known for its role in sleep regulation, delayed the onset of symptoms and reduced mortality in a mouse model of Huntington's disease, say researchers at the University of Pittsburgh School of Medicine and ...
Neuroscience
Oct 11, 2011 |
4.7 / 5 (3) |
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Dantrolene protects neurons from Huntington's disease
Huntington's disease (HD) is characterized by ongoing destruction of specific neurons within the brain. It affects a person's ability to walk, talk, and think - leading to involuntary movement and loss of muscle co-ordination. ...
Neuroscience
Nov 25, 2011 |
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