The study, which has been published in the scientific journal Cell Metabolism, shows significant changes in the brain's hormone control centre, the hypothalamus. In a series of experiments on mice, which had the mutated Huntington's ...
Apr 6, 2011
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Huntington's disease is caused by a mutation in the Huntingtin gene, a protein necessary for the proper functioning of several brain cells. Mutated, it is no longer able to perform properly: it can even become toxic for the ...
Mar 18, 2022
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Neurodegenerative diseases, like Huntington's disease and myotonic dystrophy, are often referred to as DNA repeat diseases, named because of long repeated sequences in the DNA of patients. Increasing repeat expansion length ...
Feb 27, 2020
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A breakthrough genetic discovery from researchers at the Schulich School of Medicine & Dentistry at the University of Western Ontario is unlocking new clues about why some individuals experience early onset of neurodegenerative ...
Nov 29, 2021
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Researchers from the RIKEN Brain Science Institute in Japan, in collaboration with Juntendo University and the Japan Science and Technology Agency, have discovered that a cell receptor widely involved in intracellular calcium ...
Sep 8, 2014
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Researchers believe they have learned how mutations in the gene that causes Huntington's disease kill brain cells, a finding that could open new opportunities for treating the fatal disorder. Scientists first linked the gene ...
Jun 23, 2014
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A study led by researchers at the National Institutes of Health has made a surprising connection between frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), two disorders of the nervous system, and the ...
Dec 4, 2020
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Huntington's disease—a hereditary and fatal genetic disorder—has long been considered a neuronal disease due to the permanent loss of medium spiny motor neurons, the death of which over time is responsible for the clinical ...
Aug 30, 2022
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Fingolimod, a drug used to treat multiple sclerosis, restores hippocampal synaptic plasticity and improves memory function. This is the main conclusion of a study developed by researchers at the University of Barcelona (UB) ...
Jul 14, 2015
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Huntington's disease is the most common neurodegenerative disorder controlled by a single gene and is characterized by motor and cognitive deficits and psychiatric symptoms. Currently, no treatments can stop or reverse the ...
Oct 13, 2023
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