Immunology

Scientists discover how gene mutation triggers immune disease

Scientists discovered how a gene mutation affects T cell function to promote immune disorders and then tested a treatment based on the discovery—successfully fixing donated immune cells from a 16-year-old boy with an abnormally ...

Oncology & Cancer

Cancer immunotherapy on the cusp

Glass crystals with thread-like filaments floating inside sit in the offices of two prominent immunologists. The clear blocks encase models of the structure of PD-1/PD-L1, a receptor-ligand pair that rides on the surface ...

Immunology

Understanding the origins and function of CD14+ immune cells

Dendritic cells and macrophages are immune cells that orchestrate diverse immune functions within many body tissues, including the skin. New work by A*STAR researchers and colleagues shows that CD14+ cells in the skin—long ...

Diabetes

Antibodies reverse type 1 diabetes in new immunotherapy study

Scientists at the University of North Carolina School of Medicine have used injections of antibodies to rapidly reverse the onset of Type I diabetes in mice genetically bred to develop the disease. Moreover, just two injections ...

Medical research

Worm extract found to reduce inflammation in mouse models

A team of researchers from Germany, Switzerland, Sweden and Australia has found that a substance isolated from roundworm larvae was able to reduce inflammation in the airways of mice. In their paper published in the journal ...

Immunology

New way to fight sepsis: Rev up patients' immune systems

While many people have never heard of sepsis, it causes about 250,000 deaths annually in the United States. The condition develops when an infection triggers an overwhelming immune response, ultimately wreaking havoc on the ...

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