Oncology & Cancer

Boosting the immune response against cancer

T cells are usually good at eliminating diseased cells, but they seem to fail when it comes to tumor cells. In JCI Insight, MDC teams led by Armin Rehm and Uta Höpken describe what inhibits this immune function, and how ...

Oncology & Cancer

Cancer immunotherapy capable of modulating tumor immunophenotypes

Innovations in cancer immunotherapy have achieved clinical success by considerably increasing the survival rate of patients undergoing cancer treatment. However, there still exists an unmet medical need due to the low response ...

Diseases, Conditions, Syndromes

Studies reveal key clues about COVID-19 immunity, immune recall

How does the immune system remember and recognize viral invaders it has encountered in the past? A trio of newly published studies of people infected with SARS-CoV-2, vaccinated against the virus, or both are providing tantalizing ...

Oncology & Cancer

T cell behavior determines which tumors respond to treatment

Immunotherapy unleashes the power of the immune system to fight cancer. However, for some patients, immunotherapy doesn't work, and new research may help explain why. When immune cells called T lymphocytes infiltrate malignant ...

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