News tagged with immune response
A genetically-engineered virus tested in 30 terminally-ill liver cancer patients significantly prolonged their lives, killing tumours and inhibiting the growth of new ones, scientists reported on Sunday.
Cancer Feb 10, 2013 | 4.6 / 5 (44) | 12
For the past few decades, health officials have been reporting increases in the incidence of autoimmune diseases such as multiple sclerosis (MS). Now researchers at Yale School of Medicine, Harvard Medical ...
Medical research Mar 06, 2013 | 4.4 / 5 (16) | 11 |
(HealthDay)—A new Swedish study suggests that parents who want to protect their infants from developing allergies should try a simple approach to introducing their children to the wide world of microbes: ...
Immunology May 06, 2013 | 4.7 / 5 (13) | 2 |
New research links loneliness to a number of dysfunctional immune responses, suggesting that being lonely has the potential to harm overall health.
Psychology & Psychiatry Jan 19, 2013 | 4.5 / 5 (12) | 2 |
(Medical Xpress)—Inflammatory response plays a major role in both health protection and disease generation. While the symptoms of disease-related inflammatory response have been know, scientists have not ...
Inflammatory disorders Feb 23, 2013 | 4.8 / 5 (10) | 4 |
(Medical Xpress)—An international team of scientists has discovered the mechanism by which zebrafish can re-grow brain neurons after they have suffered traumatic brain injury, and that this mechanism is ...
Medical research Nov 09, 2012 | 4.9 / 5 (9) | 3 |
Researchers in Newcastle and Singapore have identified a new type of white blood cell which activates a killing immune response to an external source providing a new potential target for vaccines for conditions such ...
Immunology Jul 27, 2012 | 5 / 5 (8) | 0 |
Breakthrough in understanding human immune response has potential for the development of new drug therapies
(Medical Xpress) -- A team of researchers at Trinity College Dublins School of Medicine has gained new insights into a protein in the human immune system that plays a key role in the protective response to infection ...
Immunology Jul 06, 2012 | 5 / 5 (6) | 0 |
Researchers at Queen Mary, University of London have discovered how a key molecule controls the body's inflammatory responses. The molecule, known as p110delta, fine-tunes inflammation to avoid excessive reactions that can ...
Immunology Sep 30, 2012 | 5 / 5 (6) | 0 |
The injection of a tiny capsule containing heat-generating cells into the abdomens of mice led those animals to burn abdominal fat and initially lose about 20 percent of belly fat after 80 days of treatment.
Medical research Sep 05, 2012 | 4.5 / 5 (6) | 0 |
Scientists at Montana State University have developed a therapeutic that has potential as a biological drug or probiotic food product to combat many of the more than 80 autoimmune disorders that affect some 23.5 million people ...
Medical research May 17, 2013 | 4.3 / 5 (6) | 0
(HealthDay)—A new vaccination approach may provide protection against genital herpes as well as other sexually transmitted infections, including HIV, according to a new study involving mice.
Medical research Oct 17, 2012 | 5 / 5 (5) | 0 |
Symptoms of an autoimmune disease disappeared after a team of scientists retrained the white blood cells. This method is extremely promising for treating diseases such as type I diabetes and multiple sclerosis.
Immunology Dec 17, 2012 | 5 / 5 (5) | 0 |
Researchers at Hospital for Special Surgery have identified a potential new target for drugs to treat patients with rheumatoid arthritis (RA), a protein known as IRHOM2. The finding could provide an effective ...
Arthritis & Rheumatism Jan 25, 2013 | 5 / 5 (5) | 0 |
As blood stem cells age, changes in the epigenome—the system that regulates which genes are switched on and which are switched off throughout the body—alter these cells in ways that lead to reduced immune ...
Medical research Feb 15, 2013 | 5 / 5 (5) | 0 |
An immune system is a collection of biological processes within an organism that protects against disease by identifying and killing pathogens and tumour cells. It detects a wide variety of agents, from viruses to parasitic worms, and needs to distinguish them from the organism's own healthy cells and tissues in order to function properly. Detection is complicated as pathogens can evolve rapidly, producing adaptations that avoid the immune system and allow the pathogens to successfully infect their hosts.
To survive this challenge, multiple mechanisms evolved that recognize and neutralize pathogens. Even simple unicellular organisms such as bacteria possess enzyme systems that protect against viral infections. Other basic immune mechanisms evolved in ancient eukaryotes and remain in their modern descendants, such as plants, fish, reptiles, and insects. These mechanisms include antimicrobial peptides called defensins, phagocytosis, and the complement system. Vertebrates such as humans have even more sophisticated defense mechanisms. The immune systems of vertebrates consist of many types of proteins, cells, organs, and tissues, which interact in an elaborate and dynamic network. As part of this more complex immune response, the human immune system adapts over time to recognise specific pathogens more efficiently. This adaptation process is referred to as "adaptive immunity" or "acquired immunity" and creates immunological memory. Immunological memory created from a primary response to a specific pathogen, provides an enhanced response to secondary encounters with that same, specific pathogen. This process of acquired immunity is the basis of vaccination.
Disorders in the immune system can result in disease. Immunodeficiency occurs when the immune system is less active than normal, resulting in recurring and life-threatening infections. Immunodeficiency can either be the result of a genetic disease, such as severe combined immunodeficiency, or be produced by pharmaceuticals or an infection, such as the acquired immune deficiency syndrome (AIDS) that is caused by the retrovirus HIV. In contrast, autoimmune diseases result from a hyperactive immune system attacking normal tissues as if they were foreign organisms. Common autoimmune diseases include Hashimoto's Thyroiditis, rheumatoid arthritis, diabetes mellitus type 1 and lupus erythematosus. Immunology covers the study of all aspects of the immune system which has significant relevance to human health and diseases. Further investigation in this field is expected to play a serious role in promotion of health and treatment of diseases.
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