Engineered T cells kill tumors but spare normal tissue in an animal model
The need to distinguish between normal cells and tumor cells is a feature that has been long sought for most types of cancer drugs. Tumor antigens, unique proteins on the surface of a tumor, are potential targets for a normal ...
Cancer
Apr 07, 2013 |
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Two-step ovarian cancer immunotherapy made from patients' own tumor shows promise
As many as three quarters of advanced ovarian cancer patients appeared to respond to a new two-step immunotherapy approach—including one patient who achieved complete remission—according research from the Perelman School ...
Cancer
Apr 06, 2013 |
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Vaccine adjuvant uses host DNA to boost pathogen recognition
Aluminum salts, or alum, have been injected into billions of people as an adjuvant to make vaccines more effective. No one knows, however, how they boost the immune response. In the March 19, 2013, issue of the Proceedings of ...
Medical research
Apr 05, 2013 |
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New HIV findings reveal genetic double-edged sword
A major international research study involving Murdoch University has found that individuals born with high numbers of a receptor known as HLA-C on their cells can naturally inhibit HIV.
HIV & AIDS
Apr 05, 2013 |
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Study reveals that chemotherapy works in an unexpected way
It's generally thought that anticancer chemotherapies work like antibiotics do, by directly killing off what's harmful. But new research published online on April 4 in the Cell Press journal Immunity shows that effective chemot ...
Immunology
Apr 04, 2013 |
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Obesity without the health problems? There could be a way
Obesity is linked to the widespread epidemics of diabetes and heart disease that plague society, but a lesser-known fact is that the weight can also lead to autoimmune disease. Now, researchers have new information about ...
Overweight and Obesity
Apr 04, 2013 |
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Hepatitis A virus discovered to cloak itself in membranes hijacked from infected cells
Viruses have historically been classified into one of two types – those with an outer lipid-containing envelope and those without an envelope. For the first time, researchers at the University of North ...
Diseases, Conditions, Syndromes
Apr 04, 2013 |
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Scissor-like enzyme points toward treatment of infectious disease
UT Southwestern Medical Center researchers report that a pathogen annually blamed for an estimated 90 million cases of food-borne illness defeats a host's immune response by using a fat-snipping enzyme to ...
Medical research
Apr 04, 2013 |
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Key link between obesity and type 2 diabetes discovered
(Medical Xpress)—New research published in the journal Cell Metabolism has identified a key mechanism in the immune system involved in the development of obesity-linked type 2 diabetes. The findings open u ...
Medical research
Apr 04, 2013 |
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Researchers reveal that immune system like a turbo-charged hybrid car
(Medical Xpress)—Trinity College Dublin scientists have made a significant breakthrough in understanding the immune system that could lead to new treatments for diseases such as sepsis and Type 2 diabetes. A team led by ...
Immunology
Apr 04, 2013 |
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Researchers probe the enigma of healing element that is also the enemy
The same factor in our immune system that is instrumental in enabling us to fight off severe and dangerous inflammatory ailments is also a player in doing the opposite at a later stage, causing the suppression of our immune ...
Immunology
Apr 03, 2013 |
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White blood cell enzyme contributes to inflammation and obesity
Many recent studies have suggested that obesity is associated with chronic inflammation in fat tissues. Researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have discovered that an ...
Inflammatory disorders
Apr 02, 2013 |
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Cholesterol-lowering eye drops could treat macular degeneration
A new study raises the intriguing possibility that drugs prescribed to lower cholesterol may be effective against macular degeneration, a blinding eye disease.
Medical research
Apr 02, 2013 |
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Promising stem cell therapy for leukemia patients
Leukemia patients receive a bone marrow transplant, which allows them to build a "new" immune system. However, this immune system not only attacks cancer cells but healthy tissue too. Special antibodies will ...
Cancer
Apr 02, 2013 |
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Comparing mouse and human immune systems: Few differences charted in map to translate mouse findings to humans
(Medical Xpress)—It is a familiar note struck when authors conclude their reports on experiments conducted in mouse models: They suggest caution when translating their findings from mouse to human. A variation ...
Medical research
Apr 02, 2013 |
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