Researchers halt autoimmune disease myasthenia gravis in mice
Working with mice, Johns Hopkins researchers say they have developed a gene-based therapy to stop the rodent equivalent of the autoimmune disease myasthenia gravis by specifically targeting the destructive immune response ...
Immunology
Oct 01, 2012 |
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Immune drug helps patients with serious kidney disorder
A drug commonly used to treat immune disorders such as lymphoma and arthritis also benefits patients with an immune disorder of the kidneys that can lead to kidney failure, according to a study appearing in an upcoming issue ...
Diseases, Conditions, Syndromes
Jul 19, 2012 |
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Fingolimod: 'Hint' of advantages in a small group of patients
The immunosuppressive drug fingolimod (trade name: Gilenya) is approved for the treatment of highly-active relapsing-remitting multiple sclerosis (RRMS) in adults. In an early benefit assessment pursuant to "Act on the Reform ...
Diseases, Conditions, Syndromes
Jul 05, 2012 |
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Successful transplantation of tissue-engineered vein in a child offers hope
The first biologically tissue-engineered vein grown from a patient's own stem cells has been successfully transplanted into a 10-year-old girl with portal vein obstruction, dramatically enhancing her quality of life. These ...
Immunology
Jun 13, 2012 |
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Conditioning regimen beneficial for kidney recipients
(HealthDay) -- Following a conditioning regimen of lymphoid irradiation (TLI) and antithymocyte globulin (ATG), the majority of HLA-matched kidney and hematopoietic cell transplant recipients can be withdrawn ...
Surgery
Mar 28, 2012 |
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Engineering whole organs: Closing in on a potential solution to the organ donor shortage?
A new technique involving the use of an artificial scaffold into which a patient's own stem cells are inserted, turning it into a fully functional organ, could offer a potential solution to the donor shortage crisis, according ...
Medical research
Mar 08, 2012 |
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New transplant method may allow kidney recipients to live life free of anti-rejection medication
New ongoing research published today in the journal Science Translational Medicine suggests organ transplant recipients may not require anti-rejection medication in the future thanks to the power of stem cells, which may pr ...
Medical research
Mar 07, 2012 |
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Stress in cells activates hepatitis viruses
People who have received a donor organ need lifelong immunosuppressant drugs to keep their immune system from attacking the foreign tissue. However, with a suppressed immune system, many infectious agents ...
Medical research
Feb 13, 2012 |
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Cochlear implants may be safe, effective for organ transplant patients
Cochlear implants may be a safe, effective option for some organ transplant patients who've lost their hearing as an unfortunate consequence of their transplant-related drug regime, researchers report.
Other
Feb 10, 2012 |
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Stop taking steroids: Kidney transplant recipients may not need long-term prednisone
Rapid discontinuation of the immunosuppressive steroid prednisone after a kidney transplant can help prevent serious side effects, according to a study appearing in an upcoming issue of the Clinical Journal of the American So ...
Other
Jan 26, 2012 |
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Weaning transplant recipients from their immunosuppressive drugs
Transplant surgeons live in the hope that one day they will be able to wean at least some of their patients off the immunosuppressive drugs that must be taken to prevent rejection of a transplanted organ. A team of researchers ...
Other
Dec 12, 2011 |
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New Stanford regimen frees kidney-transplant patients from dependency on immunosuppresant drugs
Investigators at the Stanford University School of Medicine have developed a novel protocol that allows kidney-transplant recipients to jettison their indispensable immune-suppressing drugs. The protocol could also spell ...
Medications
Oct 05, 2011 |
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Time to stop giving toxic drugs to kidney transplant patients?
Patients who receive kidney transplants must take lifelong medications that, while preventing organ rejection, can also compromise other aspects of health. Immunosuppresive drugs called calcineurin inhibitors protect transplanted ...
Other
Sep 22, 2011 |
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Continued treatment for lupus may boost survival of those patients with end-stage kidney disease
Researchers at Albert Einstein College of Medicine of Yeshiva University have shown that close supervision by rheumatologists and the use of immunosuppressant drugs improve the survival of lupus patients with end-stage kidney ...
Diseases, Conditions, Syndromes
Sep 20, 2011 |
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Substitution of brand name with generic drug proves safe for transplant recipients
A new study published in the American Journal of Transplantation reveals that substitution of a brand name immunosuppressive drug with a generic (manufactured by Sandoz) for preventing rejection of transplanted organs appear ...
Medications
Sep 13, 2011 |
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