Neuroscience

New insights into what happens in cells in early Alzheimer's

Researchers led by the ESRF, the European Synchrotron, have found that amyloid oligomers play a role in speeding up mitochondrial energetics during the early stages of Alzheimer's, in contrast to what has been previously ...

Genetics

New genes implicated in an incurable spinal disease

The discovery of eight new genes associated with a disease known as ossification of the posterior longitudinal ligament of the spine (OPLL) is a key step toward the development of effective treatments for this currently incurable ...

Oncology & Cancer

Researchers develop CAR T cells that fight prostate cancer in bone

Prostate cancer frequently metastasizes to the bone and is incurable. Moffitt Cancer Center researchers are working to identify new treatment options for this subset of patients. In a new article published today in Science ...

Medical research

Drug can spur liver regeneration in Alagille syndrome

Research led by Associate Professor Duc Dong, Ph.D., has shown for the first time that the effects of Alagille syndrome, an incurable genetic disorder that affects the liver, could be reversed with a single drug. The study, ...

Neuroscience

Targeting tau, the other protein behind Alzheimer's disease

In November, researchers reported the drug lecanemab slowed the progression of Alzheimer's disease. The effect was modest, but it has generated tremendous excitement because it was the first time a drug had been shown to ...

Oncology & Cancer

How common genetic alterations cause kidney cancer

An international group of researchers investigated why mutations often associated with renal cancer result specifically in renal cancer, instead of other cancer types.

Oncology & Cancer

Scientists discover molecule that kills pancreatic cancer cells

A research team led by scientists at Roswell Park Comprehensive Cancer Center has discovered a molecule that inhibits the growth and metastasis of pancreatic cancer cells through the iron metabolism pathway. Their findings, ...

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