A collaborative study has identified a new molecular mechanism causing rheumatoid arthritis. The researchers found that death of macrophages, an immune cell type, can trigger the disease. Moreover, they discovered how the ...
May 14, 2019
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An international research team led by Friedrich Schiller University in Jena has developed a highly sensitive cell model to study the complex effects – and side effects – of anti-inflammatory drugs, with the ultimate aim ...
Feb 22, 2019
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Some 50 to 80 percent of cancer patients taking powerful chemotherapy drugs develop diarrhea, which can be severe and in some cases life-threatening. Their problems occur when contractions in the smooth muscle lining the ...
Jun 26, 2018
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Macrophages are white blood cells involved in a variety of biological functions, from destroying infectious pathogens to repairing damaged tissue. To carry out their different roles, macrophages must first be activated and ...
May 21, 2018
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A new technique that targets drugs to specific cells could lead to improved therapies for diseases caused by an overactive immune response. The approach could help people affected by conditions such as arthritis and inflammatory ...
Sep 25, 2017
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The team, led by researchers at Imperial College London, Queen Mary University of London and Ergon Pharmaceuticals, believes the approach could offer new hope in the treatment of inflammatory conditions like arthritis, autoimmune ...
Jul 12, 2017
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In the immune system, macrophages act not only as soldiers responding to invading pathogens but also help rebuild the injured tissue once the infection is defeated. A new study by Yale Medical School researchers published ...
May 12, 2017
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Good cholesterol is well associated with lower cardiovascular disease risk, but just raising high-density lipoprotein (HDL) levels have produced disappointing results in recent clinical trials. A study published November ...
Nov 17, 2016
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In their mission to design new biomaterials that promote tissue regeneration, Drexel University researchers have identified how inflammation, when precisely controlled, is crucial to bone repair.
Jul 29, 2016
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It is well established that people with cystic fibrosis (CF) have two faulty copies of the CFTR gene, but debate continues on the question of whether certain symptoms of the airway disease are caused by the mutation or if ...
Jan 13, 2016
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