High-grade serous carcinoma is the most aggressive form of ovarian cancer and accounts for the majority of advanced-stage cases. The poor outcomes associated with the disease underscore the need for more effective treatments. ...
Mar 16, 2022
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A new study has suggested that treatment to target necroptosis in muscle fibers using a necroptosis inhibitor lessens myositis-induced muscle weakness as well as muscle cell death and inflammation in the muscles. This has ...
Mar 1, 2022
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Inhibition of Ubiquitin Specific Peptidase 47 (USP47) was identified as a novel therapeutic target for hematologic malignancies bearing mutant oncoprotein EZH2, according to scientists from the Hefei Institutes of Physical ...
Jan 27, 2022
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Our brains can distinguish highly similar patterns, thanks to a process called pattern separation. How our brains separate patterns is, however, not yet fully understood. Using a full-scale computer model of the dentate gyrus, ...
Dec 16, 2021
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In preclinical models, combining an investigational Aurora Kinase A (AURKA) inhibitor with a KRAS inhibitor or a WEE1 inhibitor showed efficacy against lung cancer cells with intrinsic or acquired resistance to KRAS inhibition, ...
Oct 7, 2021
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Schizophrenia, which can cause disrupted thought and mood, delusions and hallucinations, is among the most debilitating mental disorders and the most mysterious.
Sep 24, 2021
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Multisensory integration has been recently shown to produce a larger pupil size than unisensory constituents. Superior colliculus (SC), an important laminar nucleus in the midbrain, not only engages in spatial attention and ...
Aug 11, 2021
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Traits that allow cancer cells to escape the body's natural defense system and develop into tumors are actually a good indicator to a patient's survival prognosis, according to University of Queensland researchers.
Mar 24, 2021
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A new study has identified early risk factors that predicted heightened anxiety in young adults during the coronavirus (COVID-19) pandemic. The findings from the study, supported by the National Institutes of Health and published ...
Feb 12, 2021
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Researchers from Uppsala University show in a new study that inhibition of the protein EZH2 can reduce the growth of cancer cells in the blood cancer multiple myeloma. The reduction is caused by changes in the cancer cells' ...
Feb 12, 2021
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