Researchers at the Bellvitge Biomedical Research Institute (IDIBELL), led by Oscar Martínez Tirado participated in an international study which suggests inhibition of Sirtuin1 (SIRT1) protein as a future treatment option ...
Jan 29, 2015
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Even in its quietest moments, the brain is never "off." Instead, while under anesthesia, during slow-wave sleep, or even amid calm wakefulness, the brain's cortex maintains a cycle of activity and quiet called "up" and "down" ...
Jan 20, 2015
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(HealthDay)—Metformin's role in atherosclerosis may be inhibition of monocyte-to-macrophage differentiation via AMPK-mediated inhibition of STAT3 activation, according to research published online Dec. 31 in Diabetes.
Jan 9, 2015
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(HealthDay)—Combined inhibition of tumor necrosis factor (TNF) α and interleukin (IL)-17 is more effective than single blockade in cultures of human fibroblast-like synoviocytes (FLS), according to an experimental study ...
Jan 7, 2015
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(Medical Xpress)—Yale School of Medicine and Yale Cancer Center researchers have uncovered a genetic vulnerability of cancer cells that express telomerase—an enzyme that drives their unchecked growth—and showed that ...
Jul 18, 2014
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Researchers from IMIM (Hospital del Mar Medical Research Institute) have identified a new protein, galectin-1, as a possible therapeutic target for pancreatic cancer. For the first time they have demonstrated the effects ...
Jul 1, 2014
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The prominent role a single enzyme plays in cancer imaging has eluded researchers for years, but not anymore. This discovery could pave new avenues in nuclear medicine. The enzyme, called neutral endopeptidase (NEP), has ...
Jun 9, 2014
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Previous studies have shown the certain pesticides can increase the risk for developing Parkinson's disease. Now, UCLA researchers have now found that the strength of that risk depends on an individual's genetic makeup, which ...
Feb 3, 2014
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Using an approach combining in vivo recordings and optogenetic manipulations in mice, the researchers succeeded in showing that the inhibition of parvalbumin-expressing prefrontal interneurons triggers a chain reaction resulting ...
Nov 21, 2013
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Resting cancer cells can be selectively destroyed by inhibiting their energy metabolism. This is the recent discovery by researchers at Charité Universitätsmedizin Berlin and the Max Delbrück Center for Molecular Medicine ...
Sep 4, 2013
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