Inflammatory disorders

Targeting necroptosis for inflammatory myopathies

A new study has suggested that treatment to target necroptosis in muscle fibers using a necroptosis inhibitor lessens myositis-induced muscle weakness as well as muscle cell death and inflammation in the muscles. This has ...

Oncology & Cancer

New therapeutic target for hematologic malignancies identified

Inhibition of Ubiquitin Specific Peptidase 47 (USP47) was identified as a novel therapeutic target for hematologic malignancies bearing mutant oncoprotein EZH2, according to scientists from the Hefei Institutes of Physical ...

Neuroscience

Pupillary light reflex can be inhibited by multisensory signals

Multisensory integration has been recently shown to produce a larger pupil size than unisensory constituents. Superior colliculus (SC), an important laminar nucleus in the midbrain, not only engages in spatial attention and ...

Neuroscience

A new hope in treating neurodegenerative disease

Korean researchers have identified the inhibition of autophagy in microglia, brain immune cells. It is expected to help develop treatments for Alzheimer's disease which occur due to the inhibition of autophagy.

Oncology & Cancer

Regulation and potential drug targets of tumor-associated Tregs

According to estimates from the World Health Organization (WHO), there will be 18.1 million new cases and 9.6 million cancer deaths worldwide in 2018. Cancer is a serious disease that affects people all over the world. And ...

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