Oncology & Cancer

Mechanisms ID'd for curcumin resensitization of cancer cells

(HealthDay)—Curcumin can resensitize chemoresistant pancreatic ductal adenocarcinoma (PDAC) cells through inhibition of the polycomb repressive complex 2 (PRC2)-PVT1-c-Myc axis, according to a study published online July ...

Neuroscience

Brain connectivity after 30 may predict psychological problems

Underdevelopment of the brain network underlying inhibition—the ability to concentrate on a particular stimulus and tune out competing stimuli—after 30 years of age is associated with self-reported psychological problems, ...

Oncology & Cancer

Study identifies new target for treatment of melanoma

A Brazilian study shows that inhibition of an RNA named RMEL3, which is encoded by a previously uncharacterized gene (also named RMEL3), can reduce the viability of cultured melanoma cells by up to 95%.

Diabetes

Vildagliptin, sitagliptin have similar effects on incretin

(HealthDay)—The dipeptidyl peptidase-4 (DPP-4) inhibitors vildagliptin and sitagliptin have similar effects on incretin hormone secretion, according to a study published online June 14 in Diabetes, Obesity and Metabolism.

Psychology & Psychiatry

Study details stress-diabetes link

A Rice University study has found a link between emotional stress and diabetes, with roots in the brain's ability to control anxiety.

Cardiology

PCSK9 monoclonal antibodies show promise in ACS

(HealthDay)—Proprotein convertase subtilisin/kexin type 9 (PCSK9) monoclonal antibodies may represent a promising treatment option for acute coronary syndrome (ACS), according to a review published online March 22 in the ...

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