Immunology

Stem cell-derived intestine model mimics innate immune responses

A stem cell-derived in vitro model displays key small intestine characteristics including innate immune responses, according to a study published November 29, 2017 in the open-access journal PLOS ONE by Ying Chen and David ...

Immunology

How do cells release IL-1? After three decades, now we know

Researchers at Boston Children's Hospital have identified, for the first time, the molecule that enables immune cells to release interleukin-1 (IL-1), a key part of our innate immune response to infections. Findings were ...

Diseases, Conditions, Syndromes

Can bats help humans survive the next pandemic?

In 2003, severe acute respiratory syndrome (SARS) infected a total of 8,098 people worldwide. First reported in China, it spread rapidly through more than two dozen countries in North America, South America, Europe and Asia.

Immunology

How cytoplasmic DNA triggers inflammation in human cells

A team led by LMU's Veit Hornung has elucidated the mechanism by which human cells induce inflammation upon detection of cytoplasmic DNA. Notably, the signal network involved differs from that used in the same context in ...

Immunology

Scientists discover the 'adrenaline' of the immune system

Scientists at the Champalimaud Centre for the Unknown and the Instituto de Medicina Molecular, in Lisbon, Portugal, have discovered that neurons located at mucosal tissues can immediately detect an infection in the organism, ...

Inflammatory disorders

Hibernating control cells or why inflammations become chronic

Rheumatoid arthritis is the most common autoimmune disease of the joints. It causes a chronic inflammatory response, with the body's own immune cells attacking the joint, including the cartilage and bone. This process does ...

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