News tagged with insulin resistance

Related topics: type 2 diabetes · diabetes · metabolic syndrome · cell metabolism · fat cells

Thirdhand smoke linked to type 2 diabetes

Thirdhand smoke (THS) results when exhaled smoke gets on surfaces - clothing, hair, homes and cars. THS has been shown, in mice, to damage the liver and lungs, complicate wound-healing and cause hyperactivity. Add to this ...

Mar 02, 2016
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Insulin-secreting cells report on insulin resistance

Diabetes researchers at Sweden's Karolinska Institutet have developed a novel technique that makes it possible to monitor insulin resistance in a non-invasive manner over time in mice. The new method, presented in the journal ...

Feb 22, 2016
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Diabetes drug may prevent recurring strokes

Pioglitazone, a drug used for type 2 diabetes, may prevent recurrent stroke and heart attacks in people with insulin resistance but without diabetes. The results of the Insulin Resistance Intervention after Stroke (IRIS) ...

Feb 17, 2016
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Insulin resistance

Insulin resistance (IR) is the condition in which normal amounts of insulin are inadequate to produce a normal insulin response from fat, muscle and liver cells. Insulin resistance in fat cells reduces the effects of insulin and results in elevated hydrolysis of stored triglycerides in the absence of measures which either increase insulin sensitivity or which provide additional insulin. Increased mobilization of stored lipids in these cells elevates free fatty acids in the blood plasma. Insulin resistance in muscle cells reduces glucose uptake (and so local storage of glucose as glycogen), whereas insulin resistance in liver cells results in impaired glycogen synthesis and a failure to suppress glucose production. Elevated blood fatty acid levels (associated with insulin resistance and diabetes mellitus Type 2), reduced muscle glucose uptake, and increased liver glucose production all contribute to elevated blood glucose levels. High plasma levels of insulin and glucose due to insulin resistance are believed to be the origin of metabolic syndrome and type 2 diabetes, including its complications.

This text uses material from Wikipedia, licensed under CC BY-SA

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