News tagged with insulin sensitivity

Related topics: diabetes · type 2 diabetes · insulin resistance · metabolic syndrome

Research shows benefits, danger of Ultraman competition

A team of Florida State University researchers found that the endurance competition called the Ultraman can lead to large reductions in body fat, but also causes temporary muscle damage and potentially insulin resistance.

Nov 18, 2015
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Genetic risk score IDs insulin resistance, change in IR

(HealthDay)—A genetic risk score based on 17 established insulin resistance (IR) variants and their effect sizes (weighted IR-GRS) is associated with IR at baseline and change in IR, but does not impact the effect of lifestyle ...

Nov 13, 2015
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Insulin resistance

Insulin resistance (IR) is the condition in which normal amounts of insulin are inadequate to produce a normal insulin response from fat, muscle and liver cells. Insulin resistance in fat cells reduces the effects of insulin and results in elevated hydrolysis of stored triglycerides in the absence of measures which either increase insulin sensitivity or which provide additional insulin. Increased mobilization of stored lipids in these cells elevates free fatty acids in the blood plasma. Insulin resistance in muscle cells reduces glucose uptake (and so local storage of glucose as glycogen), whereas insulin resistance in liver cells results in impaired glycogen synthesis and a failure to suppress glucose production. Elevated blood fatty acid levels (associated with insulin resistance and diabetes mellitus Type 2), reduced muscle glucose uptake, and increased liver glucose production all contribute to elevated blood glucose levels. High plasma levels of insulin and glucose due to insulin resistance are believed to be the origin of metabolic syndrome and type 2 diabetes, including its complications.

This text uses material from Wikipedia, licensed under CC BY-SA

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