News tagged with insulin sensitivity

Related topics: diabetes , type 2 diabetes , insulin resistance , metabolic syndrome

Insulin resistance ups T2D risk, independent of BMI

(HealthDay)—A genetic score for insulin resistance is associated with lower body mass index (BMI) and with incident type 2 diabetes (T2D) even among individuals of normal weight, according to a study published ...

Jul 07, 2014
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Study finds a spoonful of cinnamon improves health

Sprinkling a spoonful of cinnamon on breakfast foods not only adds a burst of flavor but also dramatically lowers an individual's blood sugar levels, potentially reducing the chance of developing diabetes, says a new study ...

Feb 06, 2013
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Insulin resistance

Insulin resistance (IR) is the condition in which normal amounts of insulin are inadequate to produce a normal insulin response from fat, muscle and liver cells. Insulin resistance in fat cells reduces the effects of insulin and results in elevated hydrolysis of stored triglycerides in the absence of measures which either increase insulin sensitivity or which provide additional insulin. Increased mobilization of stored lipids in these cells elevates free fatty acids in the blood plasma. Insulin resistance in muscle cells reduces glucose uptake (and so local storage of glucose as glycogen), whereas insulin resistance in liver cells results in impaired glycogen synthesis and a failure to suppress glucose production. Elevated blood fatty acid levels (associated with insulin resistance and diabetes mellitus Type 2), reduced muscle glucose uptake, and increased liver glucose production all contribute to elevated blood glucose levels. High plasma levels of insulin and glucose due to insulin resistance are believed to be the origin of metabolic syndrome and type 2 diabetes, including its complications.

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