News tagged with insulin sensitivity

Study finds important factor in fat storage and energy metabolism

As part of their ongoing research on the physiologic factors that contribute to the development of obesity, Joslin Diabetes Center scientists have identified a cell cycle transcriptional co-regulator – ...

Medical research created Jan 06, 2013 | popularity 4.8 / 5 (6) | comments 0 | with audio podcast

Single gene cause of insulin sensitivity may offer insight for treating diabetes

(Medical Xpress)—The first single gene cause of increased sensitivity to the hormone insulin has been discovered by a team of Oxford University researchers.

Diabetes created Sep 12, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Treatment of sleep apnea improves glucose levels in prediabetes

Optimal treatment of sleep apnea in patients with prediabetes improves blood sugar (glucose) levels and thus can reduce cardiometabolic risk, according to a study to be presented at the ATS 2013 International Conference in ...

Sleep apnea created May 20, 2013 | popularity not rated yet | comments 0 | with audio podcast

Key link between obesity and type 2 diabetes discovered

(Medical Xpress)—New research published in the journal Cell Metabolism has identified a key mechanism in the immune system involved in the development of obesity-linked type 2 diabetes. The findings open u ...

Medical research created Apr 04, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Our internal clocks can become ticking time bombs for diabetes and obesity

If you're pulling and all-nighter to finish a term paper, a new parent up all night with a fussy baby, or simply can't sleep like you once could, then you may be snoozing on good health. That's because new research published ...

Medical research created Apr 01, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Study shows dietary fat can affect glucose levels and insulin requirements in type 1 diabetes

In a study of patients with type 1 diabetes, Joslin researchers found that dietary fat can affect glucose levels and insulin requirements. These findings, which appeared in the April edition of Diabetes Care, have major ...

Diabetes created Mar 27, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Estrogen may improve pathway-selective insulin resistance

(HealthDay)—Estrogen treatment at the time of surgical menopause may reverse aspects of pathway-selective insulin resistance in the liver associated with a high-fat diet (HFD) in mice by promoting insulin ...

Diabetes created Feb 14, 2013 | popularity not rated yet | comments 0 | with audio podcast

Long, low intensity exercise may have more health benefits relative to short, intense workouts

Standing and walking for longer stretches improves insulin sensitivity and blood lipid levels more than an hour of intense exercise each day does, but only if the calories spent in both forms of exercise are similar. The ...

Overweight and Obesity created Feb 13, 2013 | popularity 3.5 / 5 (2) | comments 0

Study finds a spoonful of cinnamon improves health

Sprinkling a spoonful of cinnamon on breakfast foods not only adds a burst of flavor but also dramatically lowers an individual's blood sugar levels, potentially reducing the chance of developing diabetes, says a new study ...

Health created Feb 06, 2013 | popularity 5 / 5 (11) | comments 0

Inactive people can achieve major health and fitness gains in a fraction of the time

With many of us struggling to get enough exercise, sport and exercise scientists at Liverpool John Moores University (LJMU) and the University of Birmingham, under the lead of Professor Anton Wagenmakers, have been working ...

Health created Feb 01, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Link found between insulin sensitivity, cells' powerhouses

If findings of a new study in mice are any indication, it might be possible to fine-tune cellular powerhouses called mitochondria, tweaking one aspect to increase insulin sensitivity, reduce body and fat ...

Medical research created Jan 29, 2013 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Brown adipose tissue beneficial for metabolism and glucose tolerance

Joslin Diabetes Center scientists have demonstrated that brown adipose tissue (BAT) has beneficial effects on glucose tolerance, body weight and metabolism. The findings, which may lead to new treatments for diabetes, appear ...

Medical research created Dec 10, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Supplements of red wine antioxidant don't help obese men

(HealthDay)—Despite showing early promise in some animal studies, supplements of resveratrol, an antioxidant found aplenty in red wine, did not improve insulin sensitivity or heart health in obese men, ...

Diabetes created Nov 28, 2012 | popularity 1 / 5 (1) | comments 0 | with audio podcast

New treatment aids weight loss, improves diabetes in monkeys

(HealthDay)—A new, lab-created antibody that mimics the action of a naturally occurring molecule causes weight loss in monkeys, researchers report.

Medical research created Nov 28, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Insomnia may raise risk of heart attack, stroke

(HealthDay)—People with insomnia may have double the chances of a heart attack or stroke as opposed to those who sleep well, a study by Taiwanese researchers suggests.

Health created Nov 05, 2012 | popularity not rated yet | comments 0 | with audio podcast

Insulin resistance

Insulin resistance (IR) is the condition in which normal amounts of insulin are inadequate to produce a normal insulin response from fat, muscle and liver cells. Insulin resistance in fat cells reduces the effects of insulin and results in elevated hydrolysis of stored triglycerides in the absence of measures which either increase insulin sensitivity or which provide additional insulin. Increased mobilization of stored lipids in these cells elevates free fatty acids in the blood plasma. Insulin resistance in muscle cells reduces glucose uptake (and so local storage of glucose as glycogen), whereas insulin resistance in liver cells results in impaired glycogen synthesis and a failure to suppress glucose production. Elevated blood fatty acid levels (associated with insulin resistance and diabetes mellitus Type 2), reduced muscle glucose uptake, and increased liver glucose production all contribute to elevated blood glucose levels. High plasma levels of insulin and glucose due to insulin resistance are believed to be the origin of metabolic syndrome and type 2 diabetes, including its complications.

For more information about Insulin resistance, read the full article at Wikipedia.
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