News tagged with interleukin 6
More reference expression data
Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. In terms of host response to a foreign pathogen, IL-6 has been shown, in mice, to be required for resistance against the bacterium, Streptococcus pneumoniae. IL-6 is also a "myokine," a cytokine produced from muscle, and is elevated in response to muscle contraction. It is significantly elevated with exercise, and precedes the appearance of other cytokines in the circulation. During exercise, it is thought to act in a hormone-like manner to mobilize extracellular substrates and/or augment substrate delivery (Petersen, J Appl Physiol 2005). Additionally, osteoblasts secrete IL-6 to stimulate osteoblast formation. Smooth muscle cells in the tunica media of many blood vessels also produce IL-6 as a pro-inflammatory cytokine. IL-6's role as an anti-inflammatory cytokine is mediated through its inhibitory effects on TNF-alpha and IL-1, and activation of IL-1ra and IL-10.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
(Medical Xpress)—For years, Paul Shaw, PhD, a researcher at Washington University School of Medicine in St. Louis, has used what he learns in fruit flies to look for markers of sleep loss in humans.
Medical research May 03, 2013 | not rated yet | 1 |
In a study to be presented on February 14 at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in San Francisco, researchers will report that variation in a gene involved in inflammation is ...
Health Feb 11, 2013 | not rated yet | 0
Low-income teenagers who have supportive role models and engage in adaptive strategies have lower levels of a marker for cardiovascular risk than low-income teens without such resources, according to a new study.
Health Dec 20, 2012 | not rated yet | 0
(HealthDay)—Being both neurotic and conscientious may be good for your health.
Psychology & Psychiatry Nov 24, 2012 | 5 / 5 (2) | 0 |
Two large international meta-analyses published Online First in The Lancet provide compelling new evidence that interleukin-6 receptor (IL6R), a protein involved in inflammatory signaling, has a causal role in the develo ...
Cardiology Mar 13, 2012 | 5 / 5 (1) | 0 |
Highly elevated platelet levels fuel tumor growth and reduce the survival of ovarian cancer patients, an international team of researchers led by scientists at The University of Texas MD Anderson Cancer center reports in ...
Cancer Feb 15, 2012 | not rated yet | 0
A number of different immunological mechanisms ensure the successful establishment and maintenance of pregnancy. Imbalance in these mechanisms is associated with adverse pregnancy outcomes. In a review published in Advances in ...
Health Jan 10, 2012 | not rated yet | 0
By digging a little deeper, researchers may have found a potential target for reversing the deadly blood infection sepsis.
Medical research Jun 10, 2011 | not rated yet | 0 |