News tagged with interleukin

Related topics: cells · immune system

Immunology: White blood cells show their stripes

For the human immune system to work effectively, the body must be able to distinguish invading pathogens, such as fungi and bacteria, from its own healthy tissue. A group of white blood cells known as dendritic cells (DCs) ...

Aug 28, 2013
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New function for a messenger molecule

ETH Zurich Assistant Professor Cornelia Halin and her colleagues have discovered a new function of the well-known messenger protein interleukin-7: it facilitates the drainage of lymph fluid from tissues. In the future, the ...

Aug 26, 2013
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Who benefits from vitamin D?

Studying the expression of genes that are dependent on vitamin D makes it possible to identify individuals who will benefit from vitamin D supplementation, shows a University of Eastern Finland study published recently in ...

Aug 13, 2013
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New signal stabilizes atherosclerotic plaques

Atherosclerosis is an inflammatory disease with accumulation of cholesterol in the vessel walls. The atherosclerotic plaque is built up throughout life and when it ruptures it leads to heart attack or stroke. T cells are ...

Jul 31, 2013
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Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blood cells (leukocytes), The term interleukine, (inter-) as a means of communication, (-leukin) deriving from the fact that many of these proteins are produced by leukocytes and act on leukocytes. The name is something of a relic though (the term was coined by Dr. Paetkau, University of Victoria); it has since been found that interleukins are produced by a wide variety of body cells. The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by helper CD4+ T lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T, B, and hematopoietic cells.

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