News tagged with interleukin

Unusual comparison nets new sleep loss marker

(Medical Xpress)—For years, Paul Shaw, PhD, a researcher at Washington University School of Medicine in St. Louis, has used what he learns in fruit flies to look for markers of sleep loss in humans.

Medical research created May 03, 2013 | popularity not rated yet | comments 1 | with audio podcast

Scientists discover molecule that does double duty in stopping asthma attacks

Scientists from Brigham and Women's Hospital are on the brink of the next treatment advancement that may spell relief for the nearly nineteen million adults and seven million children in the United States ...

Inflammatory disorders created Feb 27, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Infusion of stem cells and specially generated T-cells from same donor improves leukemia survival

In a significant advance for harnessing the immune system to treat leukemias, researchers at Fred Hutchinson Cancer Research Center for the first time have successfully infused large numbers of donor T-cells specific for ...

Cancer created Feb 27, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Scientists boost potency, reduce side effects of IL-2 protein used to treat cancer

The utility of a naturally occurring protein given, sometimes to great effect, as a drug to treat advanced cancers is limited by the severe side effects it sometimes causes. But a Stanford University School of Medicine scientist ...

Medical research created Mar 18, 2012 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Scientists identify novel pathway for T-cell activation in leprosy

UCLA researchers pinpointed a new mechanism that potently activates T-cells, the group of white blood cells that play a major role in fighting infections.

Medical research created Mar 25, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Western diet changes gut bacteria and triggers colitis in those at risk

Certain saturated fats that are common in the modern Western diet can initiate a chain of events leading to complex immune disorders such as inflammatory bowel diseases (IBD) in people with a genetic predisposition, according ...

Medical research created Jun 13, 2012 | popularity 5 / 5 (6) | comments 0 | with audio podcast

Scientists find molecule in immune system that could help treat dangerous skin cancer

Researchers from Brigham and Women's Hospital (BWH) have made a groundbreaking discovery that will shape the future of melanoma therapy. The team, led by Thomas S. Kupper, MD, chair of the BWH Department of Dermatology, and ...

Immunology created Jul 08, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Researchers identify potential new HIV vaccine/therapy target

After being infected with simian immunodeficiency virus (SIV) in a laboratory study, rhesus macaques that had more of a certain type of immune cell in their gut than others had much lower levels of the virus in their blood, ...

HIV & AIDS created May 30, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Alzheimer's disease in mice alleviated promising therapeutic approach for humans

Pathological changes typical of Alzheimer's disease were significantly reduced in mice by blockade of an immune system transmitter. A research team from Charité - Universitätsmedizin Berlin and the University ...

Alzheimer's disease & dementia created Nov 25, 2012 | popularity 5 / 5 (10) | comments 0 | with audio podcast

Using patients' own tumor-fighting cells to knock back advanced melanoma

A small, early-phase clinical trial to test the effectiveness of treating patients with advanced melanoma using billions of clones of their own tumor-fighting cells combined with a specific type of chemotherapy has shown ...

Cancer created Mar 05, 2012 | popularity 4.8 / 5 (5) | comments 0 | with audio podcast

Study discovers new targets for treating inflammatory, autoimmune diseases

Researchers have discovered a cellular pathway that promotes inflammation in diseases like asthma, rheumatoid arthritis, psoriasis, inflammatory bowel disease, and multiple sclerosis. Understanding the details of this pathway ...

Inflammatory disorders created Oct 07, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Study identifies a potential cause of Parkinson's disease

Deciphering what causes the brain cell degeneration of Parkinson's disease has remained a perplexing challenge for scientists. But a team led by scientists from The Scripps Research Institute (TSRI) has pinpointed ...

Parkinson's & Movement disorders created Nov 19, 2012 | popularity 4.3 / 5 (6) | comments 0 | with audio podcast

Researchers identify new regulator in allergic diseases

Researchers have taken a critical step in understanding how allergic reactions occur after identifying a genetic signature for regulation of a key immune hormone, interleukin (IL-13).

Immunology created Mar 28, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Cell receptor has proclivity for T helper 9 cells, airway inflammation

A research team led by Xian Chang Li, MD, PhD, Brigham and Women's Hospital (BWH) Transplantation Research Center, has shed light on how a population of lymphocytes, called CD4+ T cells, mature into various subsets of adult ...

Immunology created Jul 29, 2012 | popularity not rated yet | comments 0 | with audio podcast

Obese dieters' brain chemistry works against their weight-loss efforts

If you've been trying to lose weight and suspect your body's working against you, you may be right, according to a University of Illinois study published in Obesity.

Medical research created Jun 23, 2011 | popularity 4.3 / 5 (3) | comments 0 | with audio podcast

Interleukin

Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blood cells (leukocytes), The term interleukine, (inter-) as a means of communication, (-leukin) deriving from the fact that many of these proteins are produced by leukocytes and act on leukocytes. The name is something of a relic though (the term was coined by Dr. Paetkau, University of Victoria); it has since been found that interleukins are produced by a wide variety of body cells. The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by helper CD4+ T lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T, B, and hematopoietic cells.

For more information about Interleukin, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Related topics: cells , immune system