Scientists identify early predictors of disease progression which could speed Huntington's disease drug trials
Scientists have identified a set of tests that could help identify whether and how Huntington's disease (HD) is progressing in groups of people who are not yet showing symptoms. The latest findings from the TRACK-HD study, ...
Neuroscience
May 08, 2013 |
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Firefly protein lights up degenerating muscles, aiding muscular-dystrophy research
Stanford University School of Medicine scientists have created a mouse model of muscular dystrophy in which degenerating muscle tissue gives off visible light. The observed luminescence occurs only in damaged muscle tissue ...
Medical research
Apr 24, 2013 |
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Toxic protein build-up in blood shines light on Huntington's disease
A new light-based technique for measuring levels of the toxic protein that causes Huntington's disease (HD) has been used to demonstrate that the protein builds up gradually in blood cells. Published today ...
Neuroscience
Sep 17, 2012 |
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A better bone marrow transplant: Preventing graft-versus-host disease
Bone marrow transplant is a key treatment for patients with leukemia, lymphoma, multiple myeloma and other blood disorders.
Medical research
Mar 01, 2013 |
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Researchers discover drug target for stimulating recovery from stroke
Investigators at the Stanford University School of Medicine have shown that removing a matched set of molecules that typically help to regulate the brain's capacity for forming and eliminating connections between nerve cells ...
Neuroscience
Mar 21, 2012 |
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Investigational diabetes drug may have fewer side effects
Drugs for type 2 diabetes can contribute to weight gain, bone fractures and cardiovascular problems, but in mice, an investigational drug appears to improve insulin sensitivity without those troublesome side ...
Medical research
Jun 04, 2012 |
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New mouthwash may render cavities a thing of the past
(Medical Xpress) -- A new mouthwash developed by a microbiologist at the UCLA School of Dentistry is highly successful in targeting the harmful Streptococcus mutans bacteria that is the principal cause tooth decay and cavities.
Health
Nov 16, 2011 |
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Research identifies targeted molecular therapy for untreatable NF1 tumors
Researchers conducting a preclinical study in mice successfully used targeted molecular therapy to block mostly untreatable nerve tumors that develop in people with the genetic disorder Neurofibromatosis 1 (NF1).
Cancer
Dec 10, 2012 |
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Heart hormone helps shape fat metabolism
It's well known that exercising reduces body weight because it draws on fat stores that muscle can burn as fuel. But a new study at Sanford-Burnham Medical Research Institute (Sanford-Burnham) suggests that ...
Medical research
Feb 06, 2012 |
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Promising new antibiotic targets potentially deadly gut infections
(Medical Xpress)—Researchers at the University of Virginia School of Medicine have developed a promising new antibiotic to treat potentially deadly gastrointestinal infections without harming the beneficial probiotic bacteria ...
Diseases, Conditions, Syndromes
Apr 12, 2013 |
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New melanoma drug Zelboraf nearly doubles survival in majority of patients
Investigators from Vanderbilt-Ingram Cancer Center (VICC) and 12 other centers in the United States and Australia have found that a new drug for patients with metastatic melanoma nearly doubled median overall survival.
Cancer
Feb 22, 2012 |
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Paragazole excels in preclinical models of triple-negative breast cancer
Breast cancers that lack estrogen receptors are more difficult to treat than ER+ cancers. Research presented at the AACR Annual Meeting 2013 demonstrates an investigational drug, Paragazole, that makes triple-negative ...
Cancer
Apr 08, 2013 |
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Weight loss surgery not only shrinks waists but also affects genes
Gastric bypass surgery can drastically reduce the body weight of obese individuals in a short timeframe. For reasons that are not entirely clear, the surgery also leads to early remission of type 2 diabetes in the vast majority ...
Medical research
Apr 11, 2013 |
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AKT inhibitor AZD5363 well tolerated, yielded partial response in patients with advanced solid tumors
The investigational drug AZD5363, which has shown activity in preclinical studies, was well tolerated in humans, and two patients with advanced solid tumors showed partial response, according to data presented at the AACR ...
Cancer
Apr 08, 2013 |
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BRCA1 or BRCA2 mutation research may offer treatment option to certain patients
(Medical Xpress)—Ongoing research at the Methodist Cancer Center could reveal whether metastatic breast cancer patients with BRCA gene mutations are particularly responsive to a drug regimen that includes Veliparib, an ...
Cancer
Sep 20, 2012 |
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