An unfortunate biological "feed-forward" loop drives cartilage cells in an arthritic joint to actually contribute to progression of the disease, say researchers at Duke University and Washington University in Saint Louis.
Mar 22, 2021
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97
Substance use disorder (SUD) is an extremely difficult disorder to overcome, and many individuals with SUD return to regular use after repeated attempts to quit.
Feb 25, 2023
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96
New research from the Victor Chang Cardiac Research Institute will allow families around the world to discover if they are carrying genetic mutations that cause sudden cardiac arrest—a condition that kills 9 out of 10 victims.
Jun 9, 2022
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183
GLYX-13, a molecular cousin to ketamine, induces similar antidepressant results without the street drug side effects, reported a study funded by the National Institute of Mental Health (NIMH) that was published last month ...
May 30, 2013
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A new study suggests that the malaria drug hydroxychloroquine inhibits pathways that drive resistance to the chemotherapy agent cisplatin in head and neck cancers and restores tumor-killing effects of cisplatin in animal ...
Mar 14, 2022
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248
An epilepsy drug shows promise in an animal model at preventing tinnitus from developing after exposure to loud noise, according to a new study by researchers at the University of Pittsburgh School of Medicine. The findings, ...
May 27, 2013
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As several Neandertal genomes of high quality are now available researchers can identify genetic changes that were present in many or all Neandertals, investigate their physiological effects and look into their consequences ...
Jul 23, 2020
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181
Chronic obstructive pulmonary disease—COPD for short—is one of the most common diseases of the lung. It affects almost 300 million people worldwide, of which about three million die every year. A collective term for chronic ...
Jan 14, 2022
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19
To learn what different cells do, scientists switch them on and off and observe what the effects are. There are many methods that do this, but they all have problems: too invasive, or too slow, or not precise enough. Now, ...
Mar 23, 2016
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303
Researchers exploring the effects of a long-standing treatment for cystic fibrosis have discovered a potential new target for drugs to treat the disease, which has no cure and typically cuts decades off the lives of patients.
Jan 31, 2019
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