Researchers discover link between inherited endocrine tumor syndrome and well-studied cell pathway
(Medical Xpress)—A mutation in a protein called menin causes a hereditary cancer syndrome called MEN1 (multiple endocrine neoplasia type 1). Individuals with MEN1 are at a substantially increased risk of ...
Cancer
Apr 24, 2013 |
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Fractalkine: New protein target for controlling diabetes
Researchers at the University of California, San Diego School of Medicine have identified a previously unknown biological mechanism involved in the regulation of pancreatic islet beta cells, whose role is to produce and release ...
Diabetes
Apr 11, 2013 |
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Decreased melatonin secretion associated with higher risk of developing type 2 diabetes
With previous evidence suggesting that melatonin may have a role in glucose metabolism, researchers have found an independent association between decreased secretion of melatonin and an increased risk for the development ...
Diabetes
Apr 02, 2013 |
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Research suggests popular diabetes drugs can cause abnormal pancreatic growth in humans
(Medical Xpress)—Individuals who had taken a type of drug commonly used to treat Type 2 diabetes showed abnormalities in the pancreas, including cell proliferation, that may be associated with an increased risk of neuroendocrine ...
Diabetes
Mar 27, 2013 |
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Mini-organ would mimic pancreas to treat type 1 diabetes
(HealthDay)— A new bioengineered, miniature organ dubbed the BioHub might one day offer people with type 1 diabetes freedom from their disease.
Medical research
Mar 05, 2013 |
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Immune intervention reduces beta-cell death in type 1 diabetes
(HealthDay)—Patients recently diagnosed with type 1 diabetes have greater death of pancreatic β-cells compared with patients with long-standing diabetes, which can be reduced by treatment with teplizumab, ...
Diabetes
Feb 26, 2013 |
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Reprogramming cells to fight diabetes
For years researchers have been searching for a way to treat diabetics by reactivating their insulin-producing beta cells, with limited success. The "reprogramming" of related alpha cells into beta cells ...
Medical research
Feb 22, 2013 |
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Islet transplant may slow progression of atherosclerosis
Minimally invasive islet transplantation for patients with type 1 diabetes achieves insulin independence and reverses the progression of atherosclerosis in the first few years after transplant, according to a University of ...
Diabetes
Jan 28, 2013 |
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Researchers report islet cell advancement increases impact on transplantation
A study published in the current issue of Cell Transplantation (21:8), now freely available on-line, reports that a team of researchers in South Korea have successfully engineered islet cell clusters (ICCs) that will improv ...
Medical research
Nov 27, 2012 |
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Studies investigate oxygen's impact as a factor in transplantation
Two studies published in the current issue of Cell Transplantation (21:7), now freely available on-line, investigate the role of oxygen in cell transplantation.
Medical research
Nov 15, 2012 |
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MRI images transplanted islet cells with help of positively charged nanoparticles
In a study to investigate the detection by MRI of six kinds of positively-charged magnetic iron oxide nanoparticles designed to help monitor transplanted islet cells, a team of Japanese researchers found that the charged ...
Medical research
Oct 01, 2012 |
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Mouse pancreatic stem cells successfully differentiate into insulin producing cells
In a study to investigate how transplanted islet cells can differentiate and mature into insulin-producing pancreatic cells, a team of Japanese researchers found that using a specific set of transcription factors (proteins ...
Medical research
Sep 25, 2012 |
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Broader approach reveals genetic complexity behind diabetes genes
(Medical Xpress)—Using a new method, diabetes researchers at Lund University, Sweden, have been able to reveal more of the genetic complexity behind type 2 diabetes. The new research findings have been achieved as a result ...
Genetics
Sep 04, 2012 |
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Engineered pancreatic tissues could lead to better transplants for diabetics
Technion researchers have built pancreatic tissue with insulin-secreting cells, surrounded by a three-dimensional network of blood vessels. The engineered tissue could pave the way for improved tissue transplants to treat ...
Diabetes
Aug 15, 2012 |
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Hormone discovered that preserves insulin production and beta cell function in diabetes
(Medical Xpress) -- Researchers at Duke University Medical Center have found protective, anti-diabetic functions for a hormone that, like insulin, is produced by the islet cells of the pancreas. The new hormone was found ...
Medical research
Jul 02, 2012 |
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