Investigators at Weill Cornell Medicine have assembled the most comprehensive atlas to date of messenger RNA (mRNA) variants in the mouse and human brain. The atlas is an important new resource in understanding brain development, ...
Apr 9, 2024
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21
Memory B cells depend on autophagy for their survival, but the protein Rubicon is thought to hinder this process. Researchers from Osaka University have discovered a shorter isoform of Rubicon called RUBCN100, which enhances ...
Oct 2, 2023
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A new research paper titled "Increased expression of BRD4 isoforms long (BRD4-L) and short (BRD4-S) promotes chemotherapy resistance in high-grade serous ovarian carcinoma" has been published in Genes & Cancer.
Sep 13, 2023
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A new research paper was published in Oncotarget's, titled "Differential silencing of STAT3 isoforms leads to changes in STAT3 activation."
Apr 26, 2023
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Mutations in our genes can lead to severe problems, like colon or liver cancer. But cancer is very complex. Mutations in the same genes can lead to different subtypes of tumors in different people. Currently, scientists don't ...
Apr 10, 2023
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Proteomics is the study and analysis of proteins, including their structures, functions, interactions, and modifications within a biological system. Humans have approximately 20,000 genes that produce over a million different ...
Mar 29, 2023
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The Aging journal has published a new research paper titled Isoform-specific effects of neuronal repression of the AMPK catalytic subunit on cognitive function in aged mice.
Mar 7, 2023
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In the era of Big Data, obtaining a huge amount of information is the easy part; knowing what to do with it is another story entirely. But now, researchers from Japan have reported that a new approach to analyzing data from ...
Sep 8, 2022
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Researchers at Indiana University School of Medicine are learning more about how special regulatory T cells can impact the immune system's response and how those cells could be manipulated for potential treatments for food ...
Jun 29, 2022
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132
New research led by the University of Exeter has shed light on the complexity of gene expression in the brain by characterizing the extent of isoform diversity in the human and mouse cortex, including the identification of ...
Nov 16, 2021
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