News tagged with journal of clinical investigation
Related topics: protein , mouse model , cells , cancer cells , immune system
Small proteins in the cornea protect against bacterial infection
When it comes to germ-busting power, the eyes have it, according to a discovery by University of California, Berkeley, researchers that could lead to new, inexpensive antimicrobial drugs.
Medical research
Sep 24, 2012 |
5 / 5 (1) |
0
Cystic fibrosis disrupts pancreas two ways in CF-related diabetes
A new University of Iowa study suggests there are two root causes of a type of diabetes associated with cystic fibrosis (CF). The findings, which already have sparked a clinical trial, may guide development ...
Diabetes
Sep 17, 2012 |
5 / 5 (1) |
0
|
Toxic protein build-up in blood shines light on Huntington's disease
A new light-based technique for measuring levels of the toxic protein that causes Huntington's disease (HD) has been used to demonstrate that the protein builds up gradually in blood cells. Published today ...
Neuroscience
Sep 17, 2012 |
not rated yet |
0
|
Mathematical model may lead to safer chemotherapy
Cancer chemotherapy can be a life-saver, but it is fraught with severe side effects, among them an increased risk of infection. Until now, the major criterion for assessing this risk has been the blood cell count: if the ...
Medical research
Sep 12, 2012 |
not rated yet |
0
|
Researchers identify possible new oncogene and future therapy target
A gene that may possibly belong to an entire new family of oncogenes has been linked by researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) to the resistance ...
Cancer
Sep 11, 2012 |
5 / 5 (1) |
0
|
Metastatic 'switch' could lead to cancer therapies
(Medical Xpress)—What kills cancer patients often isn't the primary tumor; it's when the tumor metastasizes—or spreads the cancer to other areas of the body.
Cancer
Sep 11, 2012 |
not rated yet |
0
|
New genetic mechanism for controlling blood cell development and blood vessel integrity found
The protein GATA2 is known as a "master regulator" of blood cell development. When a mutation occurs in the gene that makes GATA2, serious blood diseases such as acute myeloid leukemia can result.
Genetics
Sep 10, 2012 |
not rated yet |
0
|
Researchers iron out the link between serum ferritin and diabetes
Iron overload increases the risk for insulin resistance and type 2 diabetes; however, the exact mechanisms that link the two are unknown.
Medical research
Sep 10, 2012 |
5 / 5 (1) |
0
Research finds key molecules involved in forming long-term memories
How does one's experience of an event get translated into a memory that can be accessed months, even years later? A team led by University of Pennsylvania scientists has come closer to answering that question, identifying ...
Medical research
Sep 10, 2012 |
5 / 5 (6) |
3
|
Ovarian cancer cells hijack surrounding tissues to enhance tumor growth
Tumor growth is dependent on interactions between cancer cells and adjacent normal tissue, or stroma. Stromal cells can stimulate the growth of tumor cells; however it is unclear if tumor cells can influence the stroma.
Cancer
Sep 04, 2012 |
5 / 5 (1) |
0
New research uncovers diverse metabolic roles for PML tumor suppressor gene
Two papers led by scientific teams from the Cancer Genetics Program at Beth Israel Deaconess Medical Center (BIDMC) shed new light on the genetic mechanisms underlying cellular energy and metabolism and, at the same time, ...
Cancer
Aug 30, 2012 |
not rated yet |
0
New model of muscular dystrophy provides insight into disease development
Muscular dystrophy is a complicated set of genetic diseases in which genetic mutations affect the various proteins that contribute to a complex that is required for a structural bridge between muscle cells and the extracellular ...
Medical research
Aug 27, 2012 |
5 / 5 (1) |
0
Vitamin B3 may offer new tool in fight against 'superbugs'
A new study suggests that nicotinamide, more commonly known as vitamin B3, may be able to combat some of the antibiotic-resistance staph infections that are increasingly common around the world, have killed thousands and ...
Medical research
Aug 27, 2012 |
4.8 / 5 (5) |
0
|
T cells key in atherosclerosis-linked inflammation
(HealthDay) -- In a mouse model of atherosclerosis, CD4+ T cells interact with antigen-presenting cells (APCs) in the presence of cognate antigen, leading to cell activation and proliferation and the secretion ...
Medical research
Aug 22, 2012 |
not rated yet |
0
Study identifies potential new class of drug for treating ulcerative colitis
An investigational drug currently under FDA review for the treatment of rheumatoid arthritis has now shown positive results in patients with moderate-to-severe ulcerative colitis, according to researchers at the University ...
Diseases, Conditions, Syndromes
Aug 15, 2012 |
not rated yet |
0
|
