News tagged with journal of medicinal chemistry


Marine compound discovery shows promise of improved drug treatment for COPD patients

(Medical Xpress)—Pharmacy researchers at the University of Florida have isolated a new marine compound they believe may lead to improved drug therapies for pulmonary diseases by inhibiting their progression rather than ...

Diseases, Conditions, Syndromes created Feb 28, 2013 | popularity not rated yet | comments 0

Novel designed molecules could stop colon cancer metastasis

A Basque research consortium has managed to stop the development of colon cancer and its liver metastasis in an experimental model using mice. This breakthrough, which could open new avenues for the future treatment of these ...

Cancer created Feb 14, 2013 | popularity 2 / 5 (1) | comments 1

Older and younger chronic leukemia patients may need different therapy

Doctors should use different therapies when treating older and younger patients with chronic lymphocytic leukemia, according to a new study led by researchers at the Ohio State University Comprehensive Cancer Center – Arthur ...

Cancer created Dec 12, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researchers develop novel treatment for prostate cancer

(Medical Xpress)—The work of a team of Wake Forest researchers developing a novel drug for prostate cancer treatment is featured on the cover of the Nov. 26 issue of the Journal of Medicinal Chemistry.

Cancer created Nov 29, 2012 | popularity 5 / 5 (2) | comments 0

New malaria drug requires just one dose and appears twice as effective as existing regimen

Scientists are reporting development of a new malaria drug that, in laboratory tests, has been twice as effective as the best current medicine against this global scourge and may fight off the disease with ...

Diseases, Conditions, Syndromes created Oct 17, 2012 | popularity not rated yet | comments 0

New type of drug leads to hope against resistant ovarian cancer

Scientists at USC have discovered a new type of drug for the treatment of ovarian cancer that works in a way that should not only decrease the number of doses that patients need to take, but also may make it effective for ...

Cancer created Oct 03, 2012 | popularity not rated yet | comments 0 | with audio podcast

Purdue-designed molecule one step closer to possible Alzheimer's treatment

(Medical Xpress)—A new molecule designed to treat Alzheimer's disease has significant promise and is potentially the safest to date, according to researchers.

Medical research created Oct 03, 2012 | popularity not rated yet | comments 1 | with audio podcast

Trojan horse drug therapy provides new approach to treating breast cancer

When Linda Tuttle was diagnosed with breast cancer, she never imagined her experience would inspire her colleagues to design new treatments to tackle the disease.

Cancer created Oct 02, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Discovering new uses for old drugs

With the cost of putting a single new drug on the pharmacy shelves topping a staggering $1 billion, scientists are reporting development of a way to determine if an already-approved drug might be used to treat ...

Medications created Aug 01, 2012 | popularity not rated yet | comments 0

Novel anti-malarial drug target identified

An international team of scientists, led by researchers from the Department of Pediatrics at the University of California, San Diego School of Medicine, have identified the first reported inhibitors of a key ...

Medical research created Jul 19, 2012 | popularity 4 / 5 (2) | comments 0 | with audio podcast

Researchers design new substances that might help fight Alzheimer's and Parkinson's disease

University of Granada researchers have tested melatonin analogues in rats that inhibit the enzyme nitric oxide synthase, which is involved in the development of the diseases referred above.

Medical research created Jun 13, 2012 | popularity not rated yet | comments 0

Investigational diabetes drug may have fewer side effects

Drugs for type 2 diabetes can contribute to weight gain, bone fractures and cardiovascular problems, but in mice, an investigational drug appears to improve insulin sensitivity without those troublesome side ...

Medical research created Jun 04, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Professor links gene mutations with heart disease precursors

(Medical Xpress) -- It may be easier in the future to test and potentially provide early treatment for the one in 500 people affected by hypertrophic cardiomyopathy.

Cardiology created May 17, 2012 | popularity not rated yet | comments 0 | with audio podcast

Potatoes lower blood pressure in people with obesity and hypertension without increasing weight

The first study to check the effects of eating potatoes on blood pressure in humans has concluded that two small helpings of purple potatoes (Purple Majesty) a day decreases blood pressure by about 4 percent without causing ...

Health created Feb 01, 2012 | popularity not rated yet | comments 0

Surprising pathway implicated in stuttering

Researchers at Washington University School of Medicine in St. Louis have obtained new evidence that at least some persistent stuttering is caused by mutations in a gene governing not speech, but a metabolic pathway involved ...

Genetics created Nov 22, 2011 | popularity 4.5 / 5 (2) | comments 2 | with audio podcast