A potent and selective colony stimulating factor 1 receptor kinase inhibitor IHMT-CSF1R-833 was discovered by researchers led by Prof. Liu Qingsong from the Hefei Institutes of Physical Science (HFIPS) of the Chinese Academy ...
Nov 7, 2022
0
7
Endometrial cancer is the most common type of gynecological cancer and is the fourth most common type of tumor in women in developed countries. Although it has a good prognosis if detected early, advanced and aggressive cases ...
Nov 2, 2022
0
3
More than 40 years into the HIV pandemic, scientists are still turning up clues revealing how the virus hijacks its host's cellular processes to support its own replication—and promote the long-term survival of the virus ...
UVA Health Cancer Center researchers have developed an algorithm that will improve cancer care by quickly and easily identifying patients who will benefit from powerful cancer drugs called kinase inhibitors. The algorithm ...
Oct 28, 2022
0
95
One part of the basal ganglia, known as the nucleus accumbens (NAc), is composed of medium spiny neurons (MSNs). The MSNs, in which the dopamine D1 receptor (D1R) and dopamine D2 receptor (D2R) express, are controlled by ...
Sep 29, 2022
0
13
Diabetic cardiomyopathy (DCM) is a progressive complication associated with type 2 diabetes (T2D), causing deterioration of cardiac function in diabetic patients, independent of coronary artery disease, and hypertension. ...
Sep 28, 2022
0
14
In animal studies led by researchers at Duke Cancer Institute, a drug approved to treat leukemia successfully disrupted the ability of HER2-positive breast cancer tumors from colonizing the brain.
Aug 31, 2022
0
60
Kinase activity is frequently altered in renal cell carcinoma (RCC), and tyrosine kinase inhibitors (TKIs) are part of the standard treatment strategy in patients with metastatic disease. However, there are still no established ...
Aug 17, 2022
0
15
A team of University of Michigan researchers is developing a new anti-cancer drug that is absorbed through the gut's lymphatic system rather than blood vessels, potentially outmaneuvering the molecular signaling pathways ...
Aug 17, 2022
0
134
In a study recently published in Cancer Research, a team of researchers led by C. Patrick Reynolds, M.D., Ph.D., director for the Texas Tech University Health Sciences Center (TTUHSC) School of Medicine Cancer Center, sought ...
Aug 10, 2022
0
40
