Oncology & Cancer
'Inside out' signaling promotes tumor growth
A specific immune system kinase has been found to promote tumor inflammation and progression, according to a study published in Nature Communications.
Aug 8, 2022
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News tagged with kinase
Cardiology
Study finds two protein pathways downregulated in postnatal heart
In work published today in Stem Cell Reports, researchers from the University of Minnesota Medical School discovered two signaling pathways that are downregulated in human hearts after birth. These pathways, mitogen-activated ...
Aug 4, 2022
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Medications
Chemotherapy drugs from 'rogue' online pharmacies could endanger leukemia patients
Patients seeking to purchase chemotherapy drugs online face a confusing array of websites, over half of which potentially operate unsafely or illegally, finds a new study in the July 2022 issue of JNCCN—Journal of the National ...
Jul 28, 2022
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Alzheimer's disease & dementia
Uncovering one of the driving forces of Alzheimer's disease
Alzheimer's disease, the most common form of dementia, currently has no cure or effective therapy, in part due to gaps in our understanding of how the progressive neurodegenerative disorder arises in the brain.
Jul 6, 2022
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Neuroscience
Scientists identify molecular mechanisms behind learning and memory
Patients with Alzheimer's disease (AD) have lower levels of the neuromodulator acetylcholine (ACh) in their brains. Donepezil, an AD drug, increases brain ACh levels and improves AD-associated learning deficits. Now, researchers ...
Jun 27, 2022
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Medications
Combination treatment may improve quality of life in kidney cancer
Patients with advanced kidney cancer who received a new combination treatment reported health-related quality of life outcomes that were either similar or improved, compared to patients who received standard first-line therapy, ...
Jun 24, 2022
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Medications
Researchers identify cryptic vulnerabilities in an oncoprotein that could be used in novel anti-cancer drugs
RET is a receptor protein with tyrosine kinase activity that can transfer a phosphate group from ATP to other molecules modifying their shape and function in signaling pathways that are essential to organogenesis and tissue ...
Jun 24, 2022
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Medications
Locking leukemia's cellular escape hatch
Leukemia starts in cells that would normally develop into different types of blood cells. About 61,000 people in the U.S. are diagnosed each year, and depending on the type of leukemia and the age of the patient, five-year ...
Jun 8, 2022
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Oncology & Cancer
Anti-cancer drug profiling with CancerOmicsNet
As documented in a new research paper published in Oncotarget, researchers from Louisiana State University have developed CancerOmicsNet—a graph neural network model to predict the growth rate of a cancer cell line after ...
May 19, 2022
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Medications
Imatinib shows improved outcomes for patients with severe COVID-19 in the CounterCOVID clinical trial
Patients with severe COVID-19 who were given imatinib had lower mortality rates at 90-day follow-up, according to research published at the ATS 2022 international conference.
May 18, 2022
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