Oncology & Cancer
'Inside out' signaling promotes tumor growth
A specific immune system kinase has been found to promote tumor inflammation and progression, according to a study published in Nature Communications.
Aug 8, 2022
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News tagged with kinase
Cardiology
Study finds two protein pathways downregulated in postnatal heart
In work published today in Stem Cell Reports, researchers from the University of Minnesota Medical School discovered two signaling pathways that are downregulated in human hearts after birth. These pathways, mitogen-activated ...
Aug 4, 2022
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Alzheimer's disease & dementia
Uncovering one of the driving forces of Alzheimer's disease
Alzheimer's disease, the most common form of dementia, currently has no cure or effective therapy, in part due to gaps in our understanding of how the progressive neurodegenerative disorder arises in the brain.
Jul 6, 2022
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Medications
Combination treatment may improve quality of life in kidney cancer
Patients with advanced kidney cancer who received a new combination treatment reported health-related quality of life outcomes that were either similar or improved, compared to patients who received standard first-line therapy, ...
Jun 24, 2022
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Medications
Locking leukemia's cellular escape hatch
Leukemia starts in cells that would normally develop into different types of blood cells. About 61,000 people in the U.S. are diagnosed each year, and depending on the type of leukemia and the age of the patient, five-year ...
Jun 8, 2022
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Medical research
The role of metabolic signaling in preventing atrial fibrillation
Research from the Yale School of Medicine indicates that a protein kinase that is a master regulator of cell metabolism is critical to preventing atrial fibrillation. The research appeared April 22 in the journal JCI Insight.
Apr 26, 2022
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Medications
Rewiring the biology of leukemia cells to reverse drug resistance
Researchers from Barts Cancer Institute at Queen Mary University of London have identified a way to reverse resistance to a group of cancer drugs, known as kinase inhibitors, in leukemia cells. By rewiring the inner workings ...
Apr 19, 2022
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Medications
Rilzabrutinib for blood disorder shows promise in phase 1–2 clinical trial
In people with immune thrombocytopenia (ITP), the body produces destructive antibodies against platelets in the blood, which increases the risk of bruising, bleeding, hospitalization, death, fatigue, and an impaired quality ...
Apr 15, 2022
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Oncology & Cancer
Researchers develop novel method to identify and treat aggressive early-stage lung cancers
Mount Sinai researchers have developed a novel method to identify aggressive early-stage lung cancers and target drugs known as aurora kinase inhibitors to tumors that are especially likely to respond to them. The findings, ...
Mar 24, 2022
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76
Medical research
More effective COVID-19 treatment with immune modulatory drugs
A recent study published in the Proceedings of the National Academy of Sciences by a team of researchers at the University of Colorado Anschutz Medical Campus significantly advances the understanding of a key aspect of the ...
Feb 28, 2022
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