When antibody-producing immune cells encounter infectious pathogens for the first time, they engage a signal cascade to generate a massive activation signal within seconds. The mechanisms underlying this acute initial activation ...
Nov 5, 2020
0
46
Personalized treatment options for patients with lung cancer have come a long way in the past two decades. For patients with non-small cell lung cancer, the most common subtype of lung cancer and the leading cause of cancer-related ...
Oct 16, 2020
0
45
Epileptic seizures often originate in small, localized areas of the brain where neurons abnormally fire in unison. These electrical impulses disrupt proper brain functioning and cause seizures. But what makes regions where ...
Oct 8, 2020
0
12
Like packaging designed to create a protective environment around a product, the mix of cells and fluids immediately surrounding human bone marrow provides critical protective and nourishing conditions for hematopoietic—or ...
Oct 6, 2020
0
64
Our thoughts, feelings, and movements are controlled by billions of neurons talking to each other at trillions of specialized communication points called synapses. In an in-depth study of neurons grown in laboratory petri ...
Oct 5, 2020
0
45
The effectiveness of cancer treatment is often hampered by cancer cells being heterogeneous. This is the case for EGFR-mutated lung cancer: drugs based on biomolecules of a type known as tyrosine kinase inhibitor (TKI) have ...
Oct 5, 2020
0
6
Scientists at St. Jude Children's Research Hospital have visualized previously unknown structures of the ABL kinase, offering insight for designing the next generation of targeted therapies for adult and childhood cancers. ...
Oct 2, 2020
0
70
Researchers have identified a second path to defeating chronic myelogenous leukemia, which tends to affect older adults, even in the face of resistance to existing drugs.
Sep 21, 2020
0
28
Combined use of aspirin, statins, and metformin is associated with decreased lung cancer incidence and mortality, according to a study published in the Journal of Thoracic Oncology (JTO).
Sep 17, 2020
0
5
New preclinical research from The University of Texas MD Anderson Cancer Center and BridgeBio Pharma, Inc. affiliate Navire Pharma, Inc., finds that the novel SHP2 inhibitor IACS-13909 is able to overcome multiple therapeutic-resistance ...
Sep 14, 2020
0
7
