Mutation causing wrong-way plumbing explains one type of blue-baby syndrome
Total anomalous pulmonary venous connection (TAPVC), one type of "blue baby" syndrome, is a potentially deadly congenital disorder that occurs when pulmonary veins don't connect normally to the left atrium of the heart. This ...
Medical research
May 12, 2013 |
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tPA: Clot buster and brain protector
(Medical Xpress)—Ever since its introduction in the 1990s, the "clot-busting" drug tPA has been considered a "double-edged sword" for people experiencing a stroke. It can help restore blood flow to the ...
Neuroscience
May 07, 2013 |
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Astrocyte signaling sheds light on stroke research
New research published in The Journal of Neuroscience suggests that modifying signals sent by astrocytes, our star-shaped brain cells, may help to limit the spread of damage after an ischemic brain stroke. The study in mic ...
Neuroscience
Mar 18, 2013 |
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Gene linked to respiratory distress in babies
(Medical Xpress)—Some infants are more susceptible to potentially life-threatening breathing problems after birth, and rare, inherited DNA differences may explain why, according to research at Washington ...
Pediatrics
Nov 27, 2012 |
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Lack of oxygen in cancer cells leads to growth and metastasis
(Medical Xpress)—It seems as if a tumor deprived of oxygen would shrink. However, numerous studies have shown that tumor hypoxia, in which portions of the tumor have significantly low oxygen concentrations, ...
Cancer
Sep 13, 2012 |
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Master gene affects neurons that govern breathing at birth and in adulthood
When mice are born lacking the master gene Atoh1, none breathe well and all die in the newborn period. Why and how this occurs could provide new answers about sudden infant death syndrome (SIDS), but the solution has remained ...
Neuroscience
Sep 06, 2012 |
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Modified tPA could be effective stroke treatment without bleeding risk
Even when its clot-dissolving powers are removed, the stroke drug tPA can still protect brain cells from the loss of oxygen and glucose induced by a stroke, researchers have discovered.
Neuroscience
Jul 17, 2012 |
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Study suggests smoking, but not nicotine, reduces risk for rare tumor
New research confirms an association between smoking and a reduced risk for a rare benign tumor near the brain, but the addition of smokeless tobacco to the analysis suggests nicotine is not the protective substance.
Cancer
Apr 23, 2012 |
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Team gains understanding of white matter in infants receiving heart surgery
A collaborative team of researchers at Children's National Medical Center are making progress in understanding how to protect infants needing cardiac surgery from white matter injury, which impacts the nervous system. The ...
Cardiology
Mar 08, 2012 |
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Fumarate greatly reduces heart attack damage in mice
(Medical Xpress) -- Boosting levels of the simple compound fumarate in mice significantly reduces damage from a heart attack, an Oxford University-led study has shown.
Medical research
Mar 07, 2012 |
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Researchers examine role of inflammatory mechanisms in a healing heart
(Medical Xpress) -- Virginia Commonwealth University researchers have found that an inflammatory mechanism known as inflammasome may lead to more damage in the heart following injury such as a heart attack, pointing researchers ...
Inflammatory disorders
Nov 30, 2011 |
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Mitochondria restructuring protein provides new therapeutic target for heart disease
Mitochondria are often called cellular "powerhouses" because they convert nutrients into energy. But these tiny structures also help determine cellular lifespan. Scientists at Sanford-Burnham Medical Research ...
Cardiology
Nov 17, 2011 |
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Scarring a necessary evil to prevent further damage after heart attack
After a heart attack, the portions of the heart damaged by a lack of oxygen become scar tissue. Researchers have long sought ways to avoid this scarring, which can harden the walls of the heart, lessen its ...
Cardiology
Nov 15, 2011 |
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Hope for infant brain injuries like cerebral palsy as well as multiple sclerosis
(Medical Xpress) -- In a new study published in Nature Neuroscience, a team of researchers revealed the discovery of a key protein necessary for nerve repair and could lead to the development of a treatment for brain injuri ...
Neuroscience
Jun 27, 2011 |
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Obstructive sleep apnea linked to cancer growth in mice
A new study links the intermittent interruption of breathing that occurs in patients with obstructive sleep apnea (OSA) to enhanced proliferation of melanoma cancer cells and increased tumor growth in mice, according to researchers ...
Sleep apnea
May 17, 2011 |
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