By identifying genes in patients and testing their effects in fruit flies, researchers from Sanford Burnham Prebys have found new genes that contribute to hypoplastic left heart syndrome (HLHS), a rare, life-threatening heart ...
Jul 18, 2023
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Coronary heart disease is the leading cause of adult death worldwide. The coronary angiography procedure provides the clinical standard diagnostic assessment for nearly all related clinical decision-making, from medications ...
May 10, 2023
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Almost one third of babies born with hypoplastic left heart syndrome, or HLHS, die from heart failure before their first birthday. By uncovering cellular processes that drive heart failure in these young patients, a new study ...
Apr 7, 2022
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When children are born with hypoplastic left heart syndrome (HLHS), they require a series of major surgical procedures to survive. But even with a repaired heart, as many as one in four children die from complications before ...
Aug 18, 2020
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An innovative new field of research holds the promise for pediatric cardiologists and heart surgeons to predict the future structural integrity of a child's heart valves so they can perform the best possible surgery today.
Apr 16, 2024
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Using 3D imaging, researchers in the Cardiac Center at Children's Hospital of Philadelphia (CHOP) have found that patients with hypoplastic left heart syndrome (HLHS) experiencing moderate to severe tricuspid regurgitation ...
Apr 11, 2023
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A new study published in Circulation Research provides novel insights into how mutations in the NOTCH1gene may lead to abnormal differentiation and proliferation of cardiomyocytes and contribute to ventricular hypoplasia ...
Jan 23, 2023
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Detecting a critical heart defect before birth (congenital heart defects) is less likely when a mother lives in a rural area, lives in a neighborhood with low socioeconomic status or is Hispanic, according to new research ...
May 17, 2021
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(HealthDay)—The incidence of hypertension is 12 times higher in children with surgical repair of congenital heart disease (CHD) versus healthy, matched children without CHD, according to a study published online April 8 ...
May 3, 2021
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A phase I clinical trial is the first research monitored by the Food and Drug Administration that demonstrates the potential of regenerative therapy for hypoplastic left heart syndrome (HLHS) through collecting, processing ...
Jul 23, 2019
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