News tagged with ligand

Lexatumumab tolerated for pediatric solid tumors

(HealthDay)—Lexatumumab, an agonistic, full human monoclonal antibody against tumor necrosis factor-related apoptosis-inducing ligand receptor 2, is well tolerated and may lessen certain clinical symptoms ...

Oct 16, 2012
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Target for obesity drugs comes into focus

(Medical Xpress)—Researchers at the University of Michigan have determined how the hormone leptin, an important regulator of metabolism and body weight, interacts with a key receptor in the brain.

Oct 11, 2012
popularity 5 / 5 (2) | comments 0 | with audio podcast

Jump-starting cheaper cancer vaccines

Dendritic cells (DCs)—workhorses of the immune system—derived from human embryonic stem cells (hESCs) may provide an economical way of generating off-the-shelf therapeutic vaccines against cancers, according ...

Sep 26, 2012
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Denosumab reduces burden of giant-cell tumor of the bone

Treatment with denosumab, a drug targeted against a protein that helps promote bone destruction, decreased the number of tumor giant cells in patients with giant-cell tumor of the bone, and increased new bone formation, according ...

Sep 21, 2012
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Chromosome 12 mutation linked to familial diarrhea

(HealthDay) -- An activating mutation in GUCY2C, encoding guanylate cyclase C (GC-C), is thought to cause a novel familial diarrhea syndrome seen in a Norwegian family, according to a study published online ...

Mar 22, 2012
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A silver bullet to beat cancer?

The internet is awash with stories of how silver can be used to treat cancer. Now, lab tests have shown that it is as effective as the leading chemotherapy drug - and may have fewer side-effects.

Feb 02, 2012
popularity 5 / 5 (3) | comments 0 | with audio podcast