News tagged with ligands
Study identifies how zebrafish regrow their brains
(Medical Xpress)—An international team of scientists has discovered the mechanism by which zebrafish can re-grow brain neurons after they have suffered traumatic brain injury, and that this mechanism is ...
Medical research
Nov 09, 2012 |
4.9 / 5 (9) |
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Drugs found to both prevent and treat Alzheimer's disease in mice
Researchers at USC have found that a class of pharmaceuticals can both prevent and treat Alzheimer's Disease in mice.
Alzheimer's disease & dementia
May 21, 2013 |
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Cancer therapy that boosts immune system ready for wider testing
Two clinical trials led by Johns Hopkins Kimmel Cancer Center researchers in collaboration with other medical centers, testing experimental drugs aimed at restoring the immune system's ability to spot and attack cancer, have ...
Cancer
Jun 02, 2012 |
4.6 / 5 (7) |
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A silver bullet to beat cancer?
The internet is awash with stories of how silver can be used to treat cancer. Now, lab tests have shown that it is as effective as the leading chemotherapy drug - and may have fewer side-effects.
Cancer
Feb 02, 2012 |
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Gene therapy reverses type 1 diabetes in mice
An experimental cure for Type 1 diabetes has a nearly 80 percent success rate in curing diabetic mice. The results, to be presented Saturday at The Endocrine Society's 93rd Annual Meeting in Boston, offer possible hope of ...
Medical research
Jun 06, 2011 |
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Target for obesity drugs comes into focus
(Medical Xpress)—Researchers at the University of Michigan have determined how the hormone leptin, an important regulator of metabolism and body weight, interacts with a key receptor in the brain.
Medical research
Oct 11, 2012 |
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New structure of an important immune system complex resolves a 10-year controversy
(Medical Xpress) -- Researchers at the University of Toronto and the University of Bath have resolved a longstanding controversy surrounding an important structure of the immune system that could result in ...
Medical research
May 04, 2011 |
4 / 5 (2) |
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Could engineered fatty particles help prevent AIDS?
Could engineered fatty particles help prevent AIDS? Liposomes block HIV infection in early tests; could be a cost-effective preventive for developing countries
HIV & AIDS
Sep 19, 2011 |
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Folate receptors may serve as a front door to ovarian cancer treatment
A new strategy that takes advantage of ovarian cancer's reliance on folate appears to give relapse patients extra months of life with few side effects, researchers say.
Cancer
Oct 28, 2011 |
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Do deficits in brain cannabinoids contribute to eating disorders?
A new report in Biological Psychiatry suggests that deficits in endocannabinoid function may contribute to anorexia nervosa and bulimia. Endocannabinoids are substances made by the brain that affect brain function and ch ...
Psychology & Psychiatry
Oct 31, 2011 |
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Possible new pathway can overcome glioblastoma resistance
Glioblastoma, a lethal brain cancer, is one of the most resistant to available therapies and patients typically live approximately 15 months.
Cancer
Jan 24, 2012 |
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Mechanism ID'd for benefit of stem cells in autoimmunity
(HealthDay) -- Bone marrow mesenchymal stem cells (BMMSCs) activate a mechanism involving coupling of FAS/FAS ligand to induce T cell apoptosis and immune tolerance, according to an experimental study published ...
Medical research
May 02, 2012 |
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Scientists provide detailed view of brain protein structure: Results may help improve drugs for neurological disorders
Researchers have published the first highly detailed description of how neurotensin, a neuropeptide hormone which modulates nerve cell activity in the brain, interacts with its receptor. Their results suggest that neuropeptide ...
Medical research
Oct 10, 2012 |
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Lexatumumab tolerated for pediatric solid tumors
(HealthDay)—Lexatumumab, an agonistic, full human monoclonal antibody against tumor necrosis factor-related apoptosis-inducing ligand receptor 2, is well tolerated and may lessen certain clinical symptoms ...
Cancer
Oct 16, 2012 |
5 / 5 (1) |
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Ruling the airways: Notch controls bronchial cell fates and distributions
Nestled deep within the body, the epithelial lining of the respiratory system is nonetheless seriously exposed. Its direct contact with environmental air necessitates protective mechanisms that both seal ...
Medical research
Jan 22, 2013 |
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Ligand
In coordination chemistry, a ligand is an ion or molecule (see also: functional group) that binds to a central metal atom to form a coordination complex. The bonding between metal and ligand generally involves formal donation of one or more of the ligand's electron pairs. The nature of metal-ligand bonding can range from covalent to ionic. Furthermore, the metal-ligand bond order can range from one to three. Ligands are viewed as Lewis bases, although rare cases are known involving Lewis acidic "ligands."
Metal and metalloids are bound to ligands in virtually all circumstances, although gaseous "naked" metal ions can be generated in high vacuum. Ligands in a complex dictate the reactivity of the central atom, including ligand substitution rates, the reactivity of the ligands themselves, and redox. Ligand selection is a critical consideration in many practical areas, including bioinorganic and medicinal chemistry, homogeneous catalysis, and environmental chemistry.
Ligands are classified in many ways: their charge, their size (bulk), the identity of the coordinating atom(s), and the number of electrons donated to the metal (denticity or hapticity). The size of a ligand is indicated by its cone angle.
For more information about Ligand, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
