News tagged with liver damage

When you eat matters: Study offers drug-free intervention to prevent obesity, diabetes

It turns out that when we eat may be as important as what we eat. Scientists at the Salk Institute for Biological Studies have found that regular eating times and extending the daily fasting period may override ...

Medical research created May 17, 2012 | popularity 4.8 / 5 (17) | comments 7 | with audio podcast

Adult stem cells take root in livers and repair damage

Johns Hopkins researchers have demonstrated that human liver cells derived from adult cells coaxed into an embryonic state can engraft and begin regenerating liver tissue in mice with chronic liver damage.

Medical research created May 11, 2011 | popularity 4.3 / 5 (6) | comments 2 | with audio podcast

Manipulating serotonin can promote healthy repair in chronic liver disease

(Medical Xpress) -- Publishing in the leading medical journal Nature Medicine, a team led by Newcastle University academics have identified serotonin receptors which can be targeted with drugs to enhance the natural healin ...

Medical research created Nov 28, 2011 | popularity 5 / 5 (5) | comments 1 | with audio podcast

CDC to baby boomers: Get tested for hepatitis C

(AP) -- For the first time, health officials are proposing that all baby boomers get tested for hepatitis C.

Diseases, Conditions, Syndromes created May 18, 2012 | popularity 4.7 / 5 (3) | comments 0

Antioxidant may prevent alcohol-induced liver disease

An antioxidant may prevent damage to the liver caused by excessive alcohol, according to new research from the University of Alabama at Birmingham. The findings, published online April 21, 2011, in the journal Hepatology, may po ...

Diseases, Conditions, Syndromes created May 02, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Public confused about ingredients in pain relievers

People take billions of doses of over-the-counter pain relievers like Tylenol every year, but many do not pay attention to the active ingredients they contain, such as acetaminophen, according to a new Northwestern Medicine ...

Medications created May 03, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Largest ever genetic study of liver function could point the way to new treatments

Researchers have identified a large number of areas in the human genetic code that are involved in regulating the way in which the liver functions, in a new study of over 61,000 people, published today in the journal Nature Ge ...

Genetics created Oct 16, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Estrogen fuels autoimmune liver damage

A life-threatening condition that often requires transplantation and accounts for half of all acute liver failures, autoimmune hepatitis is often precipitated by certain anesthetics and antibiotics. Researchers say these ...

Medical research created Apr 30, 2013 | popularity 5 / 5 (2) | comments 0

Entry point for hepatitis C infection identified

A molecule embedded in the membrane of human liver cells that aids in cholesterol absorption also allows the entry of hepatitis C virus, the first step in hepatitis C infection, according to research at the University of ...

Diseases, Conditions, Syndromes created Jan 24, 2012 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

NIH launches free database of drugs associated with liver injury

A free source of evidence-based information for health care professionals and for researchers studying liver injury associated with prescription and over-the-counter drugs, herbals, and dietary supplements is now available ...

Diseases, Conditions, Syndromes created Oct 12, 2012 | popularity 3 / 5 (2) | comments 0

Doubling up on cold, flu remedies may harm liver

(HealthDay)—Taking too much acetaminophen, an active ingredient in many commonly used drugs for fever and pain relief, including Tylenol, can cause liver damage, experts at the U.S. Food and Drug Administration ...

Medications created Jan 30, 2013 | popularity 3 / 5 (2) | comments 0

Alcohol metabolism causes DNA damage and triggers a breast cancer-related DNA damage response

Alcohol is known to be carcinogenic to humans in the upper aerodigestive tract, liver, colorectum, and the female breast. Evidence suggests that acetaldehyde, the primary metabolite of alcohol, plays a major role in alcohol-related ...

Health created Sep 15, 2011 | popularity 5 / 5 (1) | comments 0

Toxic liquor kills 143 in eastern India

A batch of home-brewed liquor thought to have been laced with the highly toxic chemical methanol has killed 143 people in eastern India, an official told AFP on Thursday.

Health created Dec 15, 2011 | popularity 5 / 5 (1) | comments 0

Restoring what's lost: Uncovering how liver tissue regenerates

The liver is unique among mammalian organs in its ability to regenerate after significant tissue damage or even partial surgical removal.

Medical research created Mar 12, 2012 | popularity 5 / 5 (1) | comments 0

Body building, diet supplements linked to liver damage: study

(HealthDay) -- Body-building and weight-loss products are the types of dietary supplements most likely to cause liver injury, according to a small new study.

Health created May 22, 2012 | popularity 2.5 / 5 (2) | comments 1

Hepatotoxicity

Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. The liver plays a central role in transforming and clearing chemicals and is susceptible to the toxicity from these agents. Certain medicinal agents when taken in overdoses and sometimes even when introduced within therapeutic ranges may injure the organ. Other chemical agents such as those used in laboratories and industries, natural chemicals (e.g. microcystins) and herbal remedies can also induce hepatotoxicity. Chemicals that cause liver injury are called hepatotoxins.

More than 900 drugs have been implicated in causing liver injury and it is the most common reason for a drug to be withdrawn from the market. Chemicals often cause subclinical injury to liver which manifests only as abnormal liver enzyme tests. Drug induced liver injury is responsible for 5% of all hospital admissions and 50% of all acute liver failures.

For more information about Hepatotoxicity, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.