News tagged with liver damage

When you eat matters: Study offers drug-free intervention to prevent obesity, diabetes

It turns out that when we eat may be as important as what we eat. Scientists at the Salk Institute for Biological Studies have found that regular eating times and extending the daily fasting period may override ...

Medical research created May 17, 2012 | popularity 4.8 / 5 (17) | comments 7 | with audio podcast

Entry point for hepatitis C infection identified

A molecule embedded in the membrane of human liver cells that aids in cholesterol absorption also allows the entry of hepatitis C virus, the first step in hepatitis C infection, according to research at the University of ...

Diseases, Conditions, Syndromes created Jan 24, 2012 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Largest ever genetic study of liver function could point the way to new treatments

Researchers have identified a large number of areas in the human genetic code that are involved in regulating the way in which the liver functions, in a new study of over 61,000 people, published today in the journal Nature Ge ...

Genetics created Oct 16, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Adult stem cells take root in livers and repair damage

Johns Hopkins researchers have demonstrated that human liver cells derived from adult cells coaxed into an embryonic state can engraft and begin regenerating liver tissue in mice with chronic liver damage.

Medical research created May 11, 2011 | popularity 4.3 / 5 (6) | comments 2 | with audio podcast

Human disease leptospirosis identified in new species, the banded mongoose, in Africa

(Medical Xpress)—The newest public health threat in Africa, scientists have found, is coming from a previously unknown source: the banded mongoose. Leptospirosis, the disease is called. And the banded mongoose ...

Diseases, Conditions, Syndromes created May 14, 2013 | popularity not rated yet | comments 0 | with audio podcast

Some omega-3 oils better than others for protection against liver disease

(Medical Xpress)—Research at Oregon State University has found that one particular omega-3 fatty acid has a powerful effect in preventing liver inflammation and fibrosis – common problems that are steadily rising along ...

Diseases, Conditions, Syndromes created Feb 05, 2013 | popularity not rated yet | comments 0 | with audio podcast

Liver mitochondria improve, increase after chronic alcohol feeding in mice

(Medical Xpress)—Scientists at the Keck School of Medicine of the University of Southern California (USC) have found evidence that liver mitochondria in mice adapt to become better metabolizers of alcohol and increase in ...

Medical research created Dec 21, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researchers find clue to how Hepatitis C virus harms liver

Researchers at the University of Southern California (USC) have discovered a trigger by which the Hepatitis C virus enters liver cells ─ shedding light on how this serious and potentially deadly virus can begin to damage ...

Diseases, Conditions, Syndromes created Dec 12, 2012 | popularity not rated yet | comments 0 | with audio podcast

BIDMC and Diagnostics For All create first low-cost, paper-based, point of care liver function test

A new postage stamp-sized, paper-based device could provide a simple and reliable way to monitor for liver damage at a cost of only pennies per test, say researchers at Beth Israel Deaconess Medical Center (BIDMC) and Diagnostics ...

Diseases, Conditions, Syndromes created Sep 19, 2012 | popularity not rated yet | comments 0 | with audio podcast

Molecular and protein markers discovered for liver transplant failure from hepatitis C

Researchers have discovered molecular and protein signatures that predict rapid onset of liver damage in hepatitis C patients following a liver transplant. The markers appeared soon after transplant and well before clinical ...

Diseases, Conditions, Syndromes created Aug 16, 2012 | popularity not rated yet | comments 0 | with audio podcast

Building a better Rift Valley fever vaccine

University of Texas Medical Branch researchers have significantly improved an existing experimental vaccine for Rift Valley fever virus, making possible the development of a more effective defense against the dangerous mosquito-borne ...

Medical research created Jun 27, 2012 | popularity not rated yet | comments 0 | with audio podcast

CDC to baby boomers: Get tested for hepatitis C

(AP) -- For the first time, health officials are proposing that all baby boomers get tested for hepatitis C.

Diseases, Conditions, Syndromes created May 18, 2012 | popularity 4.7 / 5 (3) | comments 0

Manipulating serotonin can promote healthy repair in chronic liver disease

(Medical Xpress) -- Publishing in the leading medical journal Nature Medicine, a team led by Newcastle University academics have identified serotonin receptors which can be targeted with drugs to enhance the natural healin ...

Medical research created Nov 28, 2011 | popularity 5 / 5 (5) | comments 1 | with audio podcast

Malaria vaccination strategy provides model for superior protection

Malaria is a devastating disease caused by the Plasmodium parasite which is transmitted to humans by infected mosquitoes. Hundreds of millions of new cases of malaria are reported each year, and there are more than 750,000 ...

Medical research created Jun 15, 2011 | popularity not rated yet | comments 0 | with audio podcast

Public confused about ingredients in pain relievers

People take billions of doses of over-the-counter pain relievers like Tylenol every year, but many do not pay attention to the active ingredients they contain, such as acetaminophen, according to a new Northwestern Medicine ...

Medications created May 03, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Hepatotoxicity

Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. The liver plays a central role in transforming and clearing chemicals and is susceptible to the toxicity from these agents. Certain medicinal agents when taken in overdoses and sometimes even when introduced within therapeutic ranges may injure the organ. Other chemical agents such as those used in laboratories and industries, natural chemicals (e.g. microcystins) and herbal remedies can also induce hepatotoxicity. Chemicals that cause liver injury are called hepatotoxins.

More than 900 drugs have been implicated in causing liver injury and it is the most common reason for a drug to be withdrawn from the market. Chemicals often cause subclinical injury to liver which manifests only as abnormal liver enzyme tests. Drug induced liver injury is responsible for 5% of all hospital admissions and 50% of all acute liver failures.

For more information about Hepatotoxicity, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.