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Paired CT scans catch chemo-killing of liver tumors in real time

Using two successive pairs of specialized CT scans, a team of Johns Hopkins and Dutch radiologists has produced real-time images of liver tumors dying from direct injection of anticancer drugs into the tumors and their surrounding ...

Cancer created Jan 01, 2013 | popularity not rated yet | comments 0 | with audio podcast

FDA approves juxtapid for rare cholesterol disorder

(HealthDay)—The U.S. Food and Drug Administration has approved the orphan drug Juxtapid (lomitapide) for patients with homozygous familial hypercholesterolemia (HoFH), for use in combination with a low-fat ...

Medications created Dec 27, 2012 | popularity not rated yet | comments 0

Ability to metabolize tamoxifen affects breast cancer outcomes, study confirms

For nearly a decade, breast cancer researchers studying the hormone therapy tamoxifen have been divided as to whether genetic differences in a liver enzyme affect the drug's effectiveness and the likelihood breast cancer ...

Cancer created Dec 27, 2012 | popularity not rated yet | comments 0 | with audio podcast

Sustained virological response linked with improved survival for patients with chronic HCV infection

Among patients with chronic hepatitis C virus infection and advanced hepatic fibrosis (development of excess fibrous connective tissue), sustained virological response (SVR) to interferon-based treatment was associated with ...

Diseases, Conditions, Syndromes created Dec 25, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Hep C cases linked to NH hospital worker rise

(AP)—Five more people have been diagnosed with the same strain of hepatitis C a former traveling hospital worker is accused of spreading through tainted needles. The total is now 44 in four states.

Diseases, Conditions, Syndromes created Dec 21, 2012 | popularity not rated yet | comments 0

Hepatitis: The hidden hazard

(HealthDay)—Of all the diseases people worry about getting, viral hepatitis is usually way down on the list. Most often it's thought of as a disease that affects only drug addicts or the sexually promiscuous. ...

Diseases, Conditions, Syndromes created Dec 21, 2012 | popularity not rated yet | comments 1

One man's harrowing battle with hepatitis C

(HealthDay)—Ted Adamson's liver had been so ravaged by the hepatitis C virus that he was nearly at the point of needing a liver transplant. Yet he had no symptoms. None. He didn't even feel tired.

Diseases, Conditions, Syndromes created Dec 21, 2012 | popularity 5 / 5 (1) | comments 0

Targeted gene silencing drugs are more than 500 times more effective with new delivery method

Small interfering RNAs (siRNAs) are a potent new drug class that can silence a disease-causing gene, but delivering them to a target cell can be challenging. An innovative delivery approach that dramatically ...

Medical research created Dec 21, 2012 | popularity 5 / 5 (2) | comments 0

The X factor in liver metabolism

After you eat, your liver switches from producing glucose to storing it. At the same time, a cellular signaling pathway known as the unfolded protein response (UPR) is transiently activated, but it is not clear how this pathway ...

Medical research created Dec 21, 2012 | popularity not rated yet | comments 0

FDA panel recommends against 1st drug for chronic fatigue syndrome

(HealthDay)—A U.S. Food and Drug Administration advisory committee on Thursday recommended against approval of the first proposed drug to treat chronic fatigue syndrome.

Medications created Dec 21, 2012 | popularity 1 / 5 (1) | comments 1 | with audio podcast

Liver mitochondria improve, increase after chronic alcohol feeding in mice

(Medical Xpress)—Scientists at the Keck School of Medicine of the University of Southern California (USC) have found evidence that liver mitochondria in mice adapt to become better metabolizers of alcohol and increase in ...

Medical research created Dec 21, 2012 | popularity not rated yet | comments 0 | with audio podcast

Transplanted genetically-modified adipose cells offer potential therapy for liver diseases

Using mesenchymal stromal cells derived from adipose (fat) tissues, genetically modified to express a bioluminescent marker, researchers in Italy have tracked cells after transplantation. The cells were followed from their ...

Medical research created Dec 20, 2012 | popularity 5 / 5 (1) | comments 0

Swiss surgeons conduct complex multiple organ transplant

Surgeons in Zurich have carried out a complex, multi-organ transplant, hospital officials said Thursday, claiming the lessons learned would benefit patients with tumours that attack multiple organs.

Surgery created Dec 20, 2012 | popularity not rated yet | comments 0

Innovative method to deliver THC: Transmucosal patch increases drug's absorption

(Medical Xpress)—An innovative delivery method for tetrahydrocannabinol, the main psychoactive constituent of Cannabis, is being developed at the University of Mississippi.

Medications created Dec 20, 2012 | popularity not rated yet | comments 0

Ability to chart the molecular progress of diabetes brings personalized medicine closer to realization

Researchers in Singapore have succeeded in tracking, for the first time, the molecular changes caused by type 2 diabetes that affect how the body handles glucose production in the liver. In a series of experiments ...

Diabetes created Dec 19, 2012 | popularity 5 / 5 (1) | comments 0