News tagged with lung adenocarcinoma

High frequency of EGFR mutations found in Asian population

Adenocarcinoma histology, female sex, never-smoking status, and Asian ethnicity have been considered the most important factors associated with EGFR mutations in non-small cell lung cancer and response to EGFR inhibitors. ...

Feb 15, 2014
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Study finds new genetic error in some lung cancers

A fine-grained scan of DNA in lung cancer cells has revealed a gene fusion – a forced merger of two normally separate genes – that spurs the cells to divide rapidly, scientists at Dana-Farber Cancer Institute and the ...

Oct 28, 2013
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New marker identified for early diagnosis of lung cancer

A protein called isocitrate dehydrogenase (IDH1) is present at high levels in lung cancers and can be detected in the blood, making it a noninvasive diagnostic marker for lung cancers, according to a study published in Clinical Ca ...

Sep 17, 2013
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After Great Dane success, cancer doc eyes brain tumors

(Medical Xpress)—Two University of Colorado Cancer Center publications set stage for K9 cancer vaccine test with human glioblastoma. Michael Graner, PhD, is a CU Cancer Center investigator and associate ...

Jun 27, 2013
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Immunohistochemistry effectively detects ALK rearrangement

ALK rearrangement has been demonstrated to be a potent oncogenic driver and a promising therapeutic target in non-small cell lung cancer (NSCLC). It defines a distinct molecular subset of NSCLC, in particular adenocarcinoma ...

Jun 25, 2013
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ASCO: Case of acquired resistance to crizotinib ID'd

(HealthDay)—A case of acquired resistance to crizotinib has been described in a patient with metastatic lung adenocarcinoma harboring a CD74-ROS1 rearrangement, according to a brief report published online ...

Jun 03, 2013
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Tumors with ALK rearrangements can harbor more mutations

The identification of potentially targetable kinase mutations has been an exciting advancement in lung cancer treatment. Although the mutations driving many lung carcinomas remain unknown, approximately 50 percent of lung ...

Apr 22, 2013
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