Ganetespib showed activity in KRAS-mutant NSCLC as monotherapy and in combinations
The investigational drug ganetespib, a synthetic second-generation Hsp90 inhibitor, slowed the growth of cancer cells taken from non-small cell lung cancer tumors with a mutation in the KRAS gene. The drug was even more active ...
Cancer
Jan 11, 2012 |
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Sensitive detection method analyzes circulating tumor cells in patients with lung cancer
Researchers have developed a method to analyze circulating tumor cells in the blood of patients with non-small cell lung cancer. This method, which can analyze a sample size as small as three cells, may allow clinicians to ...
Cancer
Jan 09, 2012 |
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Estrogen-targeting drug combo may help prevent lung cancer
A combination of drugs that target estrogen production significantly reduced the number of tobacco carcinogen-induced lung tumors in mice, according to results from a preclinical study.
Cancer
Jan 09, 2012 |
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Scientists identify lung cancer stem cells and new drug targets
Singapore scientists, headed by Dr. Bing Lim, Associate Director of Cancer Stem Cell Biology at the Genome Institute of Singapore (GIS), a research institute under the umbrella of the Agency for Science, Technology and Research ...
Cancer
Jan 06, 2012 |
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Gene fusion in lung cancer afflicting never-smokers may be target for therapy
Smoking is a well-known risk factor for lung cancer, but nearly 25% of all lung cancer patients have never smoked. In a study published online today in Genome Research, researchers have identified a previously unknown gene f ...
Genetics
Dec 22, 2011 |
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Soybean compounds enhances effects of cancer radiotherapy
A Wayne State University researcher has shown that compounds found in soybeans can make radiation treatment of lung cancer tumors more effective while helping to preserve normal tissue.
Cancer
Dec 19, 2011 |
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Scientists may be able to double efficacy of radiation therapy
Scientists may have a way to double the efficacy and reduce the side effects of radiation therapy.
Cancer
Dec 16, 2011 |
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Researchers discover hereditary predisposition of melanoma of the eye
Ohio State University researchers have discovered a hereditary cancer syndrome that predisposes certain people to a melanoma of the eye, along with lung cancer, brain cancer and possibly other types of cancer.
Ophthalmology
Dec 15, 2011 |
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Cancer from fetal exposure to carcinogens depends on dose, timing
The cancer-causing potential of fetal exposure to carcinogens can vary substantially, a recent study suggests, causing different types of problems much later in life depending on the stage of pregnancy when the fetus is exposed.
Cancer
Dec 15, 2011 |
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Milk thistle extract stops lung cancer in mice
Tissue with wound-like conditions allows tumors to grow and spread. In mouse lung cancer cells, treatment with silibinin, a major component of milk thistle, removed the molecular billboards that signal these wound-like conditions ...
Cancer
Nov 15, 2011 |
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Antifolates show promise against NSCLC subtype
Patients with non-small cell lung cancer who have mutations in the KRAS gene should respond well to the antifolate class of drugs, according to results of a recent study conducted by Quintiles comparing human lung cancer ...
Cancer
Nov 14, 2011 |
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Researchers find way to screen for broad range of cancer-causing genetic changes
Researchers in the United States have shown, for the first time, that it is possible to screen cancer patients for a broad range of cancer-causing genetic mutations as part of normal clinical practice. By identifying patients' ...
Cancer
Nov 09, 2011 |
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Test helps reduce risk of death in advanced lung cancer
Researchers at the University of Colorado Cancer Center have developed a test that identifies key biomarkers in advanced lung cancer that helped reduce the risk of death by 36 percent over a 30- month period in a recent clinical ...
Cancer
Oct 11, 2011 |
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Inhaler treatment for lung cancer
Lung cancer patients could receive safer and more efficient treatment through a system being developed by researchers at the University of Strathclyde in Glasgow.
Cancer
Oct 11, 2011 |
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New research shows PET imaging effective in predicting lung cancer outcomes
Advanced imaging with Positron Emission Tomography (PET) scans shows great promise in predicting which patients with inoperable lung cancer have more aggressive tumors and need additional treatment following standard chemotherapy/radiation ...
Cancer
Oct 05, 2011 |
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